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Parliament is calling for regulators to audit pharmaceutical companies that have made misleading statements to the public about their Covid-19 vaccines. A member of the U.K. And the move comes after Moderna was chastised for the second time in five months by a U.K.
In this article, Ben Hargreaves looks into the promise of cancer vaccines and how this treatment modality may offer advantages over existing immunotherapies in the oncology sector. One area that is gathering increasing levels of interest is the development of cancer vaccines. A broad front.
AC Immune SA has received Fast Track designation from the US Food and Drug Administration (FDA) for its anti-amyloid beta (Abeta) active immunotherapy vaccine candidate for Alzheimer’s disease. The anti-Abeta therapy “specifically targets the most toxic forms of Abeta” according to Dr Andrea Pfeifer, CEO of AC Immune SA.
According to researchers, binding nasal vaccine antigens to albumin enables them to bypass mucosal barriers, and could lead to better protection against pathogens like HIV and Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2; the virus that causes COVID-19).
A BioNTech-led Phase I trial demonstrated preliminary evidence that adjuvant autogene cevumeran, a personalised mRNA neoantigen vaccine, in combination with atezolizumab (Genentech) and mFOLFIRINOX can induce substantial T cell activity in pancreatic ductal adenocarcinoma (PDAC). Can an mRNA vaccine stimulate T cell response?
In the latest edition of What HCPs Think , CREATION.co’s Laura Marsh looks at what healthcare professionals are saying about blood clots linked to COVID-19 vaccines. This sudden increase is due to reports of rare blood clots in recipients of the COVID-19 vaccines developed by AstraZeneca and more recently Johnson & Johnson.
The UK should introduce routine vaccination for respiratory syncytial virus (RSV) to protect babies and older adults, the Joint Committee on Vaccination and Immunisation (JCVI) has recommended. This article was originally published by our sister title Pulse.
With the rapid onset of the pandemic, the race to develop a viable vaccine quickly became a race to secure access to the developed vaccines. In this article, Ben Hargreaves examines how wealth determined the winners and what is now underway to help lower-income countries gain access to the available vaccines.
The comments came in response to an article The Financial Times that claimed the company is considered changing the location of a $578 million vaccine manufacturing plant from Liverpool to Philadelphia because the new U.K. million people have had Bavarian Nordic’s vaccine in the U.S. to the U.S.
As the healthcare sector grows, there is a clear trend towards the expansion of biologic therapeutic drugs and vaccines like the one developed by Novavax. To summarise, bioproduction hurdles include the necessity to be fast, agile and, not to be understated, able to deliver safe and effective vaccines worldwide. 2021 [cited May 2022].
In the face of increasing global health challenges, the development and production of vaccines have become paramount. One critical aspect is the ability to scale up manufacturing processes to meet the growing demand for viral vector-based vaccines.
European regulators are “worried” that national regulators may have undermined trust in the Oxford University/AstraZeneca vaccine by temporarily suspending its use, despite central guidance to keep using it until a safety review has concluded later this week. . Politically motivated?
Moderna has announced its combined flu and Covid vaccine has generated strong immunogenicity in early-stage trials. Interim results from its phase 1/2 studies found the vaccine (mRNA-1083) generated antibody levels similar to or greater than flu vaccines as well as similar results to the standalone Moderna Covid jab.
The failure of the European Commission to locate text messages between its president Ursula von der Leyen and Pfizer chief executive Albert Bourla on procurement of COVID-19 vaccine has earned a rebuke from the EU Ombudsman. billion doses of Pfizer and BioNTech’s vaccine. billion doses of Pfizer and BioNTech’s vaccine.
For years, the promise of therapeutic cancer vaccines has intrigued researchers working in the oncology space. Preventative vaccines have already proven to be highly effective against certain cancer types. Preventative vaccines have already proven to be highly effective against certain cancer types. And for good reason.
A randomised clinical trial of an mRNA vaccine against norovirus will be launched in the UK by the end of October 2024, it has been announced. It will evaluate the efficacy, safety, and immunogenicity of an investigational norovirus vaccine, mRNA-1403, which if successful could be the first licensed norovirus vaccine in the world.
The shingles vaccine that has been used in the NHS since last year is associated with a reduced risk of dementia, researchers have reported. A study of more than 200,000 adults before and after the US switched from Zostavax to the Shingrix vaccine found at least a 17% reduction in dementia diagnoses.
For vaccines that target infectious diseases, as Pragya Khurana and Dr Richard Pitman of ICON explain, cost-effectiveness research can power evidence generation and decision-making that helps keep people safe. Cost-effectiveness modelling is a powerful tool in understanding the value health interventions can bring to populations.
For millions of people around the world living with infectious disease and cancer, the arrival of a new prophylactic or therapeutic vaccine on the market can be life changing. Commercialising a vaccine, even one that targets an unmet need, is a challenging task for companies.
As chief operating officer, Mullane has supported rapid expansion of the business as it branches into new geographies and business areas including the cell therapy market. • Read the full article in pharmaphorum’s Deep Dive digital magazine.
For pharma marketing teams, reading pharmaceutical marketing articles is like having a roadmap to success. These articles highlight industry trends, share real-world case studies, and provide actionable strategies to sharpen your marketing campaigns. For marketing teams, these articles are a source of inspiration and knowledge.
What HCPs think about mandatory vaccination. The practice of making vaccinations mandatory within a population has always been controversial. Historically, the first example of this was during the smallpox epidemic in the 1800s , when some European countries attempted to make vaccination against the disease compulsory.
An ingenious study from Wales suggests that the shingles vaccine can reduce the risk of developing dementia ( MedRxiv, May 25, 2023 ). That said, the idea of using shingles vaccines against dementia is extraordinary. 2, 1933 were ineligible for the Zostavax vaccination to prevent shingles, whereas those born on Sept.
Both the Pfizer/BioNTech and Oxford University/AstraZeneca COVID-19 vaccines are highly effective in reducing COVID-19 infections among older people, according to an emerging study data. There is also evidence for the Pfizer vaccine, which suggests it leads to an 83% reduction in deaths from COVID-19.
An RSV vaccine provided a high overall efficacy in older adults especially among patients with a severe lower respiratory tract infection. RSV vaccine candidate, RSVPreF3, manufactured by GSK provided a high overall efficacy in a phase 3 trial among older adults according to a press release by the manufacturer. RSV vaccine results.
The UK is switching to a different pertussis vaccine for pregnant women following advice from the Joint Committee on Vaccination and Immunisation. Analysis showed antibody levels to polio type 2 were most affected by the maternal vaccination. In 2022/23, pertussis vaccine coverage was 60.7%
In this article the artificial intelligence program ChatGPT is interviewed about antimicrobial stewardship. BCPS, BCIDP Article posted 6 June 2023 Antimicrobial resistance (AMR) has emerged as a global healthcare crisis, threatening our ability to effectively treat infections and safeguard public health. Gauthier, Pharm.D.,
In this article five tips for incoming PGY2 pharmacy residents is provided. BCPS, BCIDP Article posted: 12 May 2023 The ASHP pharmacy residency match phases 1 and 2 have come to a close. Core resources can include society guidelines, ACCP Self Assessment Program chapters , review articles, key specialty books (e.g.,
Article posted 13 June 2022. There are even journal articles about how to tweet while attending scientific meetings. The frequency of Twitter posts for new research papers mirrors that of news articles, both peaking quickly and hardly mentioned a year later. Authored by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP.
The UK is switching to a different pertussis vaccine for pregnant women following advice from the Joint Committee on Vaccination and Immunisation. Analysis showed antibody levels to polio type 2 were most affected by the maternal vaccination. In 2022/23, pertussis vaccine coverage was 60.7%
For example, some pharmacists offer flu shots and other vaccinations to their patients. —————————————————- This article is an update from a previous article from 2019 , with new contributions thanks to Gayle A. Brazeau, Ph.D.,
This has been a long time coming and there are countless reasons why I believe virtual collaboration and medical education are here to stay, long after there is a vaccine for COVID-19 and physical distancing guidelines have been lifted. The convenience of virtual collaboration. Time and cost-savings.
In this article antimicrobial stewardship in the United Kingdom is discussed. Article posted 1 August 2022. At the same time, there were multiple competing priorities, such as managing the bone infection caseloads, implementing changes to departmental IPC practice, vaccination programmes and new COVID-19 treatments. BCPS, BCIDP.
Telepharmacy utilizes technology to deliver pharmacy services in an innovative way, according to an article published in Integrated Pharmacy Research and Practice. Instead, pharmacists may focus on more complex responsibilities, including patient counseling, medication therapy management, vaccinations, and other clinical services.
Pre-conception Covid-19 vaccination has been shown to have no impact on the chance of miscarriage for heterosexual couples. The findings, published in the journal Human Reproduction , suggest that vaccinated couples had a slightly lower rate of miscarriage compared to unvaccinated individuals. The risk dropped to 22.1%
As an example, Article 81.1 However, Article 81.2 These criteria appear to reflect Article 14-a of the existing EMA regulation governing conditional marketing authorisation, a provision that was the basis on which all COVID-19 vaccines have been authorised to date. This is unquestionably a laudable intention.
Despite this overlap, this article addresses the main challenges for industry and firms, and those for pharmaceutical microbiologists, separately, focusing on some of the difficult and often overlooked hurdles relating to quality assurance (QA) and quality control (QC) of licensed and marketed pharmaceutical drug products.
This article summarises the most important lessons learnt during 2020 – 2021. During the first half of 2020, surveys indicated that doctors would be reluctant to attend physical meetings in 2021, indicating preferences based mainly on fear of contracting COVID-19 and availability of vaccines. yes, if vaccines are available; 15.8%
Merck is not alone, with a number of companies making deals to leverage the growing pipeline of therapeutic candidates developed in China, such as Bavarian Nordic’s agreement to progress a potential RSV vaccine developed by Nuance Pharma. Evolving regulatory landscape.
In my last article, I outlined the inflection point facing the pharmaceutical industry in digital health and the digital transformation of its clinical and commercial operations. In March 2020 Pfizer began collaborating with BioNTech on a vaccine for COVID-19 and 269 days later it received emergency use authorisation from the FDA.
I saw a statistic in a Health Europe article, published in September this year, which reported that 81% of patients do not feel listened to by pharma companies. Later, he built the external relationships in the field of Hepatitis C, before becoming the Global Therapeutic Area Communications Leader Infectious Diseases and Vaccines.
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