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In this short article, René Holm, Professor in pharmaceutical physical chemistry at the University of Southern Denmark, provides a few examples of how a rational formulation design for a cyclodextrin solution can be defined for some important parameters. Solving the taxing problems of taxanes?
In this article we do a quick run down on IDstewardship for the end of 2022. . Article Posted 26 December 2022. As we all take a breath before heading into a new year in 2023, this article is provided as a look back and checkpoint in the life of IDstewardship.com, LearnAntibiotics.com, and the IDstewardship social media profiles.
BCPS, BCIDP Article Posted May 2023 There are many infectious diseases conferences and meetings that take place around the world each year. On this webpage, a list of antimicrobial stewardship and infectious diseases conferences and meetings is provided. List Composed By: Timothy P. Gauthier, Pharm.D.,
Novel device opens blood-brain barrier to deliver chemotherapy Intratumoural delivery The current trial was designed to evaluate the combination of intratumoural DNX-2401 followed by intravenous pembrolizumab therapy. An increase in PD-1 checkpoint expression was seen following the treatment via intratumoural delivery.
Article: Key developments: mRNA vaccines and therapeutics … Method and results of the Phase I trial The intravenously delivered mRNA vaccine was safe and generated substantial neoantigen-specific T cells in half of unselected patients with resectable PDAC, the study reported.
Chemotherapy still accounted for 72.6% Chemotherapy still plays a significant role in oncology treatment, accounting for 72.6% While all of the top ten best-selling oncology drugs in the US in 2019 were innovative therapies, four out of the top ten best-selling oncology drugs in China were for conventional chemotherapy. “In
Immunotherapy in oncology “The addition of pembrolizumab to chemotherapy represents a new frontline therapeutic option for patients with primary advanced or recurrent endometrial carcinoma” Moreover, last week saw US regulatory approval of a combination treatment for endometrial cancer : KEYTRUDA (pembrolizumab) plus chemotherapy.
neoadjuvant or adjuvant chemotherapy vs. adjuvant endocrine therapy for the prevention of recurrence). Read more about these challenges and the next steps in PQA’s work to advance quality OAM use in PQA CEO Micah Cost’s recent article in Managed Healthcare Executive. Here are four key challenges to standardized measurement.
At six months, all patients had no evidence of a tumour, allowing them to skip the chemotherapy and/or surgery that would normally be their next treatment. • Read the full article in pharmaphorum’s Deep Dive digital magazine.
If you are experiencing nausea and vomiting after surgery or cancer treatment , such as chemotherapy and radiation, your doctor may prescribe a medication called ondansetron (brand name: Zofran ). Some of the uses of ondansetron (Zofran) may not be listed in this article. What is ondansetron (Zofran)? What is ondansetron (Zofran)?
4,5 Polypharmacy – daily use of five or more drugs – is common in these patients and increases the risk of DRPs, which can result in adverse outcomes such as postoperative complications, chemotherapy toxicities and functional decline. 10,11 This can be due to side effects of chemotherapy or the addition of certain supportive care medications.
In this article, we delve into the world of infusion pharmacy, exploring salary prospects, job satisfaction, market demand, and career flexibility. From chemotherapy to nutrition support and infectious disease treatments, infusion pharmacists play a vital role in delivering specialized care directly to patients.
In this article is the conversation pharmaphorum had with Professor Nicole Concin, ESGO president, gynaecological oncologist, and professor for translational research in gynaecological oncology, at Medizinische Universität Innsbruck, Austria.
A recent Institute for Safe Medication Practices (ISMP) article breaks the numerous risks associated with manual sterile compounding processes into three main categories: Potential for contamination, leading to possible patient infections. It’s one of the riskiest processes in the pharmacy department.
She told me I had advanced breast cancer and urged me to drive down to the local emergency room immediately to get additional tests and start chemotherapy that weekend. DOWNLOAD THE FULL ARTICLE HERE. A week later, still in pain, I saw the breast surgeon. When my family and I needed them, they brushed off our concerns.
NB: in Part I of this article, notions of lower-pricing intentionality and comparative global opportunities were explored. Single Technology Appraisal: Sugemalimab with chemotherapy for untreated metastatic non-small-cell lung cancer ID4001. Meeting of the Oncologic Drugs Advisory Committee. National Institute for Clinical Excellence.
In July 2021, the French temporary authorisation for use (Autorisation Temporaire d’Utilisation, ATU) programme was the subject of a major reform, initially published within the 2021 healthcare plan on the 14th December 2020 (Article 78 – La Loi de financement de la sécurité sociale , FSSL).
In this article, we will explore the symptoms, causes, and treatment options for selective hearing loss. Medications: Some medications, such as antibiotics and chemotherapy drugs, can cause hearing loss as a side effect.
Traditionally, cancer patients are treated using “one size fits all” interventions like chemotherapy, radiotherapy and surgery. Below is a high- level overview of a typical CAR-T journey that can illustrate this complexity: Click here to read the full article. These vary in their effectiveness and result in damage to healthy tissues.
For instance, in oncology, agentic AI can process data from medical records, genetic profiles and treatment responses to recommend personalised chemotherapy protocols, potentially improving outcomes and minimising side effects. A version of this article was originally published by our sister publication Healthcare Leader.
In this article, you’ll discover: What myo-inositol is and how it supports our health. 8) More will be discussed about each of these, further on in this article. 1) (Learn more in my article about blood sugar imbalances and Hashimoto’s.). To learn more about depression and Hashimoto’s , please see my article.
Chemotherapy agents: Chemotherapy agents can lead to constipation in a variety of ways such as slowing the movements of the intestinal tract or creating inflammation that disrupts digestive function. You can read my article on turmeric for more information on this herb. Please note: do not ingest the castor oil!
It is known as an antineoplastic (chemotherapy) agent, a disease-modifying antirheumatic drug ( DMARD ), and an immunosuppressant agent. Methotrexate has distinct mechanisms of action for its use as chemotherapy versus immunosuppression in autoimmune diseases. This can minimize the risk of drug interactions.
They are prescribed to increase appetite in patients receiving chemotherapy. The Food and Drug Administration (FDA) approved the drug to treat seizures associated with Lennox-Gastaut syndrome and Dravet syndrome. Two other medications, dronabinol and nabilone, are synthetically produced to mimic THC.
This article includes personal experiences collated by us, and from others, which we hope will be a useful source of information for anyone taking Avastin. At the end of the article, Juliette Buttimore, Lead Clinical Nurse Specialist for NF2, based at Addenbrooke’s Hospital, gives some medical input.
This article discusses the main SPuMoNI accomplishments. 6 (Note: The terms “pharmaceutical” and “pharma” interchangeably employ throughout this article.) Mexican Governor: Cancer Children Given Water Instead of Chemotherapy.” Horacio Gonzalez-Velez, Ph.D. 1 Smart Pharmaceutical Manufacturing. SPuMoNI homepage. 30 June 2016.
6,7 The evidence is less conclusive for other settings, including reduced-intensity conditioning, triple alkylator chemotherapy or haplo-identical transplant. Conclusion This article provides a step-by-step overview of how to perform therapeutic drug monitoring based on the recent EBMT position paper.
Cisplatin Cisplatin is a chemotherapy drug used to treat certain types of cancers. When to talk to a healthcare provider about furosemide interactions While this article provides an overview of furosemide interactions, it is not a complete list of every possible interaction.
Thanks again for the article and for listening to a pharmacist who struggles every day with the meaning of his job. Skeptical Pharmacist #4: Medications are important in ER, urgent care, chemotherapy, pain control, but we have become dependent on them for everything! It’s so sad and I’m disappointed in being a part of this.
Ondansetron (brand name Zofran) is a medication commonly used to treat nausea and vomiting caused by cancer drug treatments like chemotherapy and radiation therapy. Still, research suggests this medicine may cause gastrointestinal symptoms, such as diarrhea, loose stools, and constipation.
As stated in a previous article, the Rapid Response Team is a group of individuals trained to handle patient, visitor, or employee emergencies in the hospital. Lecturing About Chemo I was presenting a lecture on chemotherapy products to a bunch of nurses. Getting A Stretcher It happened unexpectedly.
After surgery, strategic combinations of radiotherapy, chemotherapy like temozolomide, and other forms of treatment, such as immunotherapy or the use of an electric field cap, are employed. For example, radiotherapy and chemotherapy together entails up to six month? Two weeks later, patients began standard radiation and chemotherapy.
I have written extensively on iodine in this article ). If you have read my article on dental triggers , you know that there are better ways to prevent and heal dental decay. An article published in the journal Food and Chemical Toxicology reported that there can be up to 4.5, Canada, and parts of the U.K. ounces, or roughly 4.2
4 Notably, microbiome therapies have strong potential in onco-haematology, where antibiotic and chemotherapy-derived loss of gut diversity is predictive of mortality in patients who have undergone an allogeneic haematopoietic stem cell transplant, as well as GvHD occurrence and infection. eClinicalMedicine. 2023; 62:102111.
A recent article set out the measures required and recommended a structured review of prescribed medicines to enable rapid identification and management of potentially problematic medications. Chemotherapy-induced nausea and vomiting (CINV) can be acute, delayed or anticipatory. article (accessed November 2022).
The group adopted a positive opinion for Tremelimumab AstraZeneca (tremelimumab), to treat metastatic non-small cell lung cancer (NSCLC) in combination with Imfinzi (durvalumab) and platinum-based chemotherapy. This rare genetic disorder causes muscle weakness and is often fatal. Conclusions of referrals.
It also plays an important role in managing our oxidative stress within the thyroid, through a complex relationship with iodine, which I’ll discuss in more detail in this article. In this article, you’ll discover: The link between selenium and thyroid health. How selenium supplementation can reduce your symptoms.
Since then, there have been many articles and findings underscoring this point: fatigue can linger on even after a person normalizes their thyroid hormone levels. I’ll be sharing more in future articles and upcoming books, but for this article, let’s talk briefly about the carnitine and metabolic connections seen in other conditions.
They note that these drugs have both anti-inflammatory and anti-proliferative activity in cancer cells: “Previous studies have found that statins suppress cancer progression and micrometastasis in conjunction with chemotherapy. The anticancer properties of statins have been found in various cancers. ” That’s a bit technical.
The trial at that time involved high doses of vitamin D with chemotherapy, and began with chemo, then surgery, recuperation, more chemo, and finally radiation. Disclaimer : This article contains an abridged, unofficial summary of an FDA regulator’s presentation at a conference that has not been vetted by the agency. It is important.
When to talk to a healthcare provider about ondansetron interactions This article is only a partial list of ondansetron interactions. Ondansetron is available as an injection, an oral solution, an oral tablet, and an orally-disintegrating tablet.
While it can be used to manage many mental health conditions, including bipolar disorder and schizophrenia , it also plays a role in the prevention and treatment of chemotherapy-induced nausea and vomiting.
This article discusses breast cancer facts and stats by age, sex, and ethnicity, as well as risk factors and survival rates. ACS , 2023) Chemotherapy: This includes medications that patients take orally or intravenously. Chemotherapy can cause side effects, including diarrhea, hair loss, and fatigue. ( What is breast cancer ?
The committee has recommended that Rubraca (rucaparib camsylate) should no longer be used as third-line treatment for cancers of the ovary, fallopian tubes or peritoneum with a BRCA mutation in patients whose cancer has come back after at least two platinum-based chemotherapies and who cannot have further platinum-based therapy.
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