Remove Adverse Reactions Remove Events Remove Immunization
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How pharmacists can counsel patients on a bad reaction to a new medication

The Checkup by Singlecare

The first step in identifying or managing a medication reaction is knowing what you’re dealing with. Drug reactions may be immunologic or non-immunologic. Meaning, they may be caused by the immune system or other factors. . Immunologic reactions. Nonimmunologic reactions. Most common culprits of reactions.

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FDA approves first gene therapy for high-risk early bladder cancer

European Pharmaceutical Review

The failure to achieve a complete response (CR), or the disappearance of all signs of cancer as seen on cystoscopy, biopsied tissue, and urine, is associated with an increased risk of death or a disease-worsening event. Without treatment, the cancer can invade, damage tissues and organs, and spread through the body.

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EC approves Libtayo® for metastatic cervical cancer

European Pharmaceutical Review

Immune-mediated adverse reactions (ARs) occurred in 21 percent of patients treated with Libtayo ® and led to permanent discontinuation in 4.6 The most common immune-mediated ARs were hypothyroidism (6.8 percent), hyperthyroidism (3 percent), immune-mediated pneumonitis (2.6 percent), immune-mediated hepatitis (2.4

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Health Canada grants expanded authorisation for Novavax’s Covid-19 vaccine

Pharmaceutical Technology

According to data from Phase III trials, the booster dose elicited greater immune responses to levels in line with or over those linked to protection against Covid-19. Additionally, data from these trials showed that local and systemic reactions following the booster dosing lasted for a median duration of nearly two days.

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Europe approves Roche’s Tecentriq liver cancer combination

pharmaphorum

Grade 3–4 adverse events occurred in 57% of people receiving Tecentriq and Avastin and 55% of people receiving sorafenib. The most frequent serious adverse reactions for the combination, occurring in 2% or more of patients, were bleeding in the gastrointestinal tract and fever.

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Novel injectable bispecific antibody epcoritamab approved in EU and UK for advanced lymphoma

Hospital Pharmacy Europe

It is designed to simultaneously bind to both the cluster of differentiation (CD)3 proteins on immune T cells and the CD20 proteins on cancerous B cells and activate the T cell to destroy the B cell. Four patients (2.4%) experienced a fatal adverse reaction – ICANS in one patient (0.6%) and pneumonia in three patients (1.8%).

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FDA slaps hold on trials of Gilead’s CD47 drug magrolimab

pharmaphorum

The regulatory move applies only to trials of magrolimab given alongside Bristol-Myers Squibb’s Vidaza (azacitidine), and stems from an “imbalance” in investigator-reported serious adverse events between study arms, said the drugmaker.

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