Hospital Pharmacy Europe

JANUARY 24, 2024

Reports of serious adverse reactions to fluoroquinolone antibiotics have included tendinitis or tendon rupture, muscle pain, muscle weakness, joint pain, joint swelling, peripheral neuropathy and central nervous system effects. Fluoroquinolones use should be discontinued at the first signs of a serious adverse reaction.

Adverse Reactions 105

Adverse Reactions Hospitals 105

Drug Topics

JANUARY 9, 2023

Patients with a history of multisystem inflammatory syndrome in children (MIS-C) completed a questionnaire about adverse reactions following COVID-19 vaccination, and no serious adverse events were recorded.

Adverse Reactions 98

Adverse Reactions Vaccines 98

Pharmaceutical Technology

MAY 19, 2023

Blurred vision and eye redness are the most common adverse reactions observed with Miebo. The two 57-day, double-masked, multi-centre, saline-controlled, randomised trials were conducted in 1,217 people with DED history and clinical signs of Meibomian gland dysfunction, a major cause of development and disease progression.

FDA 133

FDA Adverse Reactions 133

STAT

JANUARY 31, 2024

and globally, for monitoring adverse reactions after a drug is on the market — one that will require extensive changes to address. Experts say that the Singulair incident highlights a flawed system, both in the U.S. “The question is, how safe do you want to be?”

Adverse Reactions 121

Adverse Reactions FDA Labelling Hospitals 121

Pharmacy Times

NOVEMBER 8, 2024

Brivudine is more effective in treating herpes zoster and does not increase the risk of adverse reactions.

Adverse Reactions 70

Adverse Reactions 70

Pharmacy Times

SEPTEMBER 22, 2022

Pharmacist education also helps prevent adverse reactions, maximizes outcomes for the symptomless disease.

Adverse Reactions 73

Adverse Reactions 73

STAT

MAY 9, 2023

It turns out that one of the supplements recommended by the health coach has adverse reactions with a medication prescribed by his doctor. He goes to the emergency room, where they immediately ask him about medications and supplements he’s taking. The health coach never asked John about his medications. Read the rest…

Adverse Reactions 102

Adverse Reactions Hospitals 102

The Checkup by Singlecare

DECEMBER 29, 2022

Nonimmunologic reactions. Nonimmunologic reactions are reactions that don’t involve the immune system and are not typically considered true allergic reactions. Instead, these non-allergic adverse reactions may be caused by the drug itself or unknown reasons. Most common culprits of reactions.

Adverse Reactions 98

Adverse Reactions Chemotherapy Immunization Dosage 98

Pharmacy Times

SEPTEMBER 16, 2024

Pharmacists can help identify potential drug-drug interactions and adverse reactions, and advise patients when to seek further treatment

Adverse Reactions 65

Adverse Reactions 65

pharmaphorum

DECEMBER 9, 2020

The most common adverse reactions seen in a trial cohort of 38,000 patients were at injection sites (84.1%) followed by fatigue (62.9%) and headache (55.1%), and serious adverse reactions occurred in 0% to 4.6% of participants.

Vaccines 111

Vaccines FDA Adverse Reactions Documentation 111

Hospital Pharmacy Europe

SEPTEMBER 4, 2023

For patient medication education, ChatGPT provided a well-organised and detailed list of therapeutic indications, dosing regimens and common adverse reactions for each medication. In addition, ChatGPT did not guide patients on necessary monitoring items and lifestyle changes.

Adverse Reactions 98

Adverse Reactions Hospitals 98

Hospital Pharmacy Europe

SEPTEMBER 4, 2023

For patient medication education, ChatGPT provided a well-organised and detailed list of therapeutic indications, dosing regimens and common adverse reactions for each medication. In addition, ChatGPT did not guide patients on necessary monitoring items and lifestyle changes.

Adverse Reactions 98

Adverse Reactions Hospitals 98

Pharmacy Times

MAY 7, 2024

Riello, PharmD, BCPS, discusses the adverse events associated with hepatic encephalopathy (HE) treatments and the importance of encouraging patients to continue first-line medications despite adverse reactions to prevent HE recurrence.

Adverse Reactions 65

Adverse Reactions 65

Pharmaceutical Technology

JANUARY 13, 2023

Diarrhoea, decreased appetite, constipation, fatigue, musculoskeletal pain, neutropenia, vomiting, anaemia, leukopenia, thrombocytopenia, increased transaminases, nausea, and alopecia are the most common adverse reactions observed in the trial.

Chemotherapy 128

Chemotherapy Adverse Reactions 128

European Pharmaceutical Review

NOVEMBER 21, 2022

The most common adverse reactions (ARs) in 10 percent or more of patients were respiratory tract infection (RTI), viral infection, diarrhoea, dyspepsia, cough, arthralgia, arthritis and peripheral edema. Serious adverse reactions (SARs) were reported in 13 percent (3/24) of patients who received the mAb.

Adverse Reactions 111

Adverse Reactions Labelling 111

European Pharmaceutical Review

JANUARY 18, 2023

To date, most solicited adverse reactions were mild or moderate. The most commonly reported solicited adverse reactions in the mRNA-1345 group were injection site pain, fatigue, headache, myalgia, and arthralgia. The trial showed the mRNA vaccine was well tolerated with no safety concerns identified.

Vaccines 105

Vaccines Adverse Reactions 105

Hospital Pharmacy Europe

JANUARY 26, 2023

Commonly reported adverse effects were generally mild to moderate in severity e.g., injection site pain, fatigue, headache, myalgia and arthralgia. In fact, only 4% of systemic adverse reactions reported for the vaccine were grade 3 or higher (i.e., of localised adverse reactions, at grade 3 or above.

Adverse Reactions 98

Adverse Reactions Vaccines Hospitals 98

Pharma Times

FEBRUARY 15, 2024

CLM-HT01 improved blood pressure and minimised adverse reactions in patients

Adverse Reactions 56

Adverse Reactions 56

European Pharmaceutical Review

OCTOBER 18, 2023

However, in the trials, the only observed adverse reaction for the treatment was diarrhoea. Overall, the data showed that XPHOZAH significantly reduced elevated serum phosphorus in patients receiving maintenance hemodialysis.

FDA 119

FDA Adverse Reactions Labelling 119

pharmaphorum

JANUARY 18, 2021

While no vaccine or medical procedure is without risk, the risk of a serious adverse reaction is very small, according to the department. At last count, California had recorded almost 3 million COVID-19 cases, with just over 33,000 deaths, placing it among the worst affected states in the US.

Vaccines 136

Vaccines Adverse Reactions FDA 136

European Pharmaceutical Review

JULY 20, 2022

1 But while data on adverse reactions is rightly used to help with these decisions, there is currently no additional modelling on the positive impact regulatory action could have on public health. Withdrawing drugs over safety concerns requires careful analysis of the health benefits and risks by regulators. Study focus.

Adverse Reactions 97

Adverse Reactions Vaccines Hospitals 97

pharmaphorum

SEPTEMBER 10, 2020

That could be important if it takes longer than expected to bring vaccines and antibodies to market, said a spokesman for the companies, pointing to the news this week that AstraZeneca has halted phase 3 trials of its COVID-19 vaccine candidate AZD1222 after a serious adverse reaction in one patient.

Vaccines 133

Vaccines Adverse Reactions Immunization 133

Hospital Pharmacy Europe

MAY 25, 2023

‘Almost a third of adverse reactions to medicines could be prevented with the introduction of genetic testing… This has the potential to transform our safety monitoring activities – enabling us to meet a real need by using high-quality patient data to reduce side effects of medicines.’

Adverse Reactions 98

Adverse Reactions Hospitals 98

Pharmaceutical Technology

MARCH 23, 2023

Diarrhoea, rash, pyrexia, nausea, musculoskeletal pain, fatigue and pruritus are the most common adverse reactions observed in patients treated with Zynyz. Partial response was seen in 22 patients and complete response in 12 patients.

FDA 98

FDA Adverse Reactions Compounding Chemotherapy 98

pharmaphorum

OCTOBER 26, 2020

US trials of AstraZeneca’s experimental COVID-19 vaccine AZD1222 have been cleared to restart by the FDA, several weeks after testing was suspended following a serious adverse reaction in one patient who received the shot.

Vaccines 95

Vaccines Adverse Reactions FDA 95

Pharmaceutical Technology

MAY 23, 2023

Dizziness, flushing, eye oedema and peripheral oedema are the most common adverse reactions for Ayvakit. Ayvakit showed improvements in disease symptoms and measures of mast cell burden compared to placebo. The company is now offering Ayvakit at a recommended 25mg once-a-day dose for adults with ISM.

FDA 98

FDA Adverse Reactions Labelling 98

European Pharmaceutical Review

NOVEMBER 23, 2022

The most common adverse reactions (AR) associated with Hemgenix included liver enzyme elevations (transaminitis), headache, mild infusion-related reactions and flu-like symptoms. Patients should be monitored for adverse infusion reactions and transaminitis in their blood.

FDA 128

FDA Adverse Reactions 128

Pharmaceutical Technology

FEBRUARY 5, 2023

Colitis, neutropenic colitis, diarrhoea, vomiting, neutropenia, febrile neutropenia, pneumonia, and abdominal pain are the most frequent serious adverse reactions observed in the TROPiCS-02 study. “We thank the physicians, patients and their families who put their trust in the TROPiCS-02 study and helped make this milestone possible.”

FDA 105

FDA Adverse Reactions Chemotherapy Labelling 105

Pharmaceutical Technology

JULY 6, 2022

Tenderness/pain at the injection site, headache, myalgia, fatigue and malaise were the most common adverse reactions reported. Furthermore, the vaccine was found to be well-tolerated in the initial safety findings from the study.

Vaccines 105

Vaccines Adverse Reactions 105

Pharmaceutical Technology

DECEMBER 7, 2022

A reduced number of serious and severe adverse reactions (AR) were reported and balanced between the vaccine and placebo arms. . Effectiveness was backed by clinical efficacy showing that the vaccine offered an overall 79.5% clinical protective efficacy when the Delta variant of the virus was prevalent.

Vaccines 105

Vaccines Adverse Reactions 105

Pharmaceutical Technology

NOVEMBER 25, 2022

Nausea, fatigue, vomiting, reduced neutrophil count, alopecia and anaemia among others were observed to be the most prevalent adverse reactions. The safety profile of Enhertu in this trial was in line with those seen in prior studies without any new safety concerns reported.

Adverse Reactions 105

Adverse Reactions Chemotherapy Labelling 105

Pharmaceutical Technology

FEBRUARY 20, 2023

Vitreous floaters, ocular discomfort, conjunctival hemorrhage, and neovascular AMD were the most common adverse reactions observed in patients receiving Syfovre. Syfovre’s safety profile is well-demonstrated after approximately 12,000 injections over 24 months.

FDA 98

FDA Adverse Reactions Immunization 98

Pharmaceutical Technology

MARCH 1, 2023

Rash pruritic, leukopenia, myalgia, injection site pruritus, neutropenia, fatigue, and constipation were the typical adverse reactions observed in the patients treated with Kevzara. The trial met its primary endpoint, with 28% of patients treated with Kevzara achieving sustained remission compared to 10% for placebo at 52 weeks.

FDA 98

FDA Adverse Reactions 98

European Pharmaceutical Review

NOVEMBER 13, 2023

In these clinical trials, the most common adverse reactions were diarrhoea, thrombocytopaenia, nausea, headache, dizziness, fatigue, asthenia, abdominal pain and cough. This trial aimed to evaluate the efficacy and safety of momelotinib versus ruxolitinib for myelofibrosis in those who had not received a prior JAK-inhibitor therapy.

Adverse Reactions 109

Adverse Reactions Pharmaceutical Companies Pharmaceutical Companies 109

European Pharmaceutical Review

JANUARY 8, 2024

Healthcare professionals are asked to report any suspected adverse reactions. . ▼ This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. The post Innovative biologic for myasthenia gravis granted European approval appeared first on European Pharmaceutical Review.

Adverse Reactions 98

Adverse Reactions 98

European Pharmaceutical Review

DECEMBER 19, 2022

The most common adverse reactions (ARs) included bladder discharge, fatigue, bladder spasm, urinary urgency, haematuria (presence of blood in urine), chills, fever, and painful urination. Overall, 51 percent of patients achieved a CR. The median duration of response was 9.7

FDA 110

FDA Adverse Reactions Immunization Vaccines 110

European Pharmaceutical Review

JUNE 2, 2023

The new Intracellular Drug Delivery Centre CPI’s Intracellular Drug Delivery Centre will help predict the stability, efficacy, performance and any potential adverse reactions of RNA vaccines and therapeutics. This will help unlock the potential of RNA-based medicines, creating greater access to cost-effective vaccines and therapeutics.

Adverse Reactions 105

Adverse Reactions Vaccines 105