Trending Articles

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FDA Approves Ensifentrine for Treatment of COPD

Drug Topics

The first-in-class selective dual PDE3 and PDE4 inhibitor from Verona Pharma is the first inhaled product with a novel mechanism of action approved to treat COPD in over 20 years.

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By the numbers: America’s alcohol-related health problems are rising fast

STAT

In the pit of the pandemic, with no one to see and nowhere to go, and horrors unfolding daily outside the front door, there was for many a reliable bright spot: the 5 p.m. drink that would mark the end of the workday. Drinking, which was already on the rise before 2020, became a coping mechanism for overburdened parents, burnt-out workers, the traumatized, and the bored.

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Slideshow: Everything You Need to Know About the US Bird Flu Outbreak

Drug Topics

In a webinar conducted by the National Foundation for Infectious Diseases (NFID), experts gathered to publicly address the ongoing bird flu outbreak across many US states.

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Three months into bird flu outbreak in U.S. dairy cows, experts see deep-rooted problems in response

STAT

Three months since an outbreak of avian influenza in U.S. dairy cattle was declared, the country is failing to take the necessary steps to get in front of the virus and possibly contain its spread among cows, according to interviews with more than a dozen experts and current and former government officials. The country still does not have a sufficient testing infrastructure in place, nor a full understanding of how the virus is moving within herds and to new herds, experts say.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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BENEFIT Trial Results Show Quadruplet Regimen for NDMM TI May Require Weighing Efficacy vs Safety

Pharmacy Times

The quadruplet regimen added bortezomib to the current standard of care, which is a triplet regimen of isatuximab, lenalidomide, and dexamethasone for patients with transplant-ineligible, newly diagnosed multiple myeloma (NDMM TI).

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Zealand Pharma rakes in $1bn in funding for obesity drugs

pharmaphorum

Fresh from reporting encouraging results with its obesity drug candidate petrelintide, Zealand Pharma has raised an impressive $1 billion from a new share offering.The Danish biotech started the fundraising process earlier this week with an expectation of raising $900 million but easily overshot that target, evidence once again of huge investor interest in companies developing a new generation of obesity drugs.

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The Supreme Court appears set to reject Idaho’s near-total abortion ban

STAT

The Supreme Court appears ready to allow emergency abortions in Idaho, according to a document obtained by Bloomberg Law. The opinion was inadvertently posted to the court’s website briefly on Wednesday, Bloomberg reported. It is unclear whether it is the final version of the decision in Idaho v. United States, but suggests that the court will dismiss Idaho’s appeal of a lower court order.

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Education on Screening for Type 1 Diabetes Can Facilitate Earlier Treatment

Pharmacy Times

Teplizumab (Tzield; Sanofi) has the potential to delay type 1 diabetes and the onset of stage 3 diabetes, but must be started in stage 1 of the disease.

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‘Skinny jabs’: weight-loss drugs set for new boom as generic versions emerge

The Guardian - Pharmaceutical Industry

Alternatives to costly Wegovy and Saxenda will make such treatments more widely available worldwide Ozempic maker invests $4bn to meet US ‘skinny jab’ demand Medicines that enable dramatic weight loss are set to experience a new boom in uptake, experts have said, as the first generic versions hit the market this week at a lower cost than the original drugs.

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Amazon consolidates Clinic telehealth service into Amazon One Medical offering

Fierce Healthcare

Amazon continues to evolve its healthcare business more than a year after spending $3.9 billion on a primary care company. | Amazon continues to evolve its healthcare business more than a year after spending $3.9 billion on a primary care company. The online retail giant is now folding its Amazon Clinic telehealth service into its One Medical primary care platform.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Weekend ICYMI: June 17 to June 21

Drug Topics

In case you missed it, this week we had news about migraine myths, the ongoing bird flu outbreak, improving vaccine hesitancy, and more.

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FDA Commissioner Says the United States Is Failing the Type 2 Diabetes Epidemic

Pharmacy Times

With improved technology and innovations for diabetes, it is essential for health care providers and health agencies to collaborate to combat rising rates of diabetes.

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Watch out, GSK. Gilead’s twice-yearly PrEP drug shows 100% efficacy for HIV prevention

Fierce Pharma

For the first time, an HIV PrEP drug candidate has shown zero infections in a phase 3 trial. | For the first time, an HIV PrEP drug candidate has shown zero infections in a phase 3 trial. For Gilead, it serves as one of two pieces for a potential FDA filing. For GSK, it means a major competitor could be looming around the corner.

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HHS lowers 64 prescription drug prices under Medicare rebate program

Fierce Healthcare

Medicare enrollees will pay less for 64 prescription drugs from July though the end of September because drug companies raised prices faster than the rate of inflation, the Centers for Medicare &am | Medicare enrollees will see lower prices this quarter for certain drugs treating cancer and genetic disorders under action unveiled by CMS.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Teva Pharmaceuticals Launches Liraglutide Injection 1.8 mg, First Generic GLP-1 in the US

Drug Topics

The Victoza generic is approved for use in adults and children aged 10 years and older.

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Michigan launches first effort of its kind to detect silent bird flu infections in farmworkers

STAT

Michigan has led the nation in making inroads with its farmers as it has worked to contain spread of H5N1 bird flu infections in dairy cows. Now the state’s health authorities are trying to do the same in looking for undetected infections among farmworkers. The Michigan Department of Health and Human Services is working with an undisclosed number of farms to try to assess the risk to workers of becoming infected with the virus, which has spread to at least 25 farms in the state in the pas

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Digital twins in healthcare and drug discovery: From idea to success stories

pharmaphorum

Explore how digital twins are transforming healthcare and drug discovery, with success stories showcasing their impact in the biopharma industry. Learn about their journey from concept to real-world applications.

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Study: Ultraviolet-B Radiation Could Improve Widespread Vitamin D Deficiency

Pharmacy Times

Ambient-UVB radiation could improve 25(OH)D prediction in the future, improving widespread vitamin D deficiencies among non-White individuals.

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Teladoc research shows AI-powered 'nudges' can improve diabetes members' engagement, health outcomes

Fierce Healthcare

Artificial intelligence can play a key role in diabetes management programs by enabling more personalized health "nudges" for members, which drives higher engagement and better health outcomes, acc | Artificial intelligence can play a key role in diabetes management programs by enabling more personalized health "nudges" for members, which drives higher engagement and better health outcomes, according to new data released by Teladoc Health.

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AstraZeneca’s Tagrisso receives approval in Japan for lung cancer

Pharmaceutical Technology

AstraZeneca has received Japanese approval for Tagrisso plus chemotherapy as first-line treatment for non-small cell lung cancer (NSCLC).

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The 42 best books and podcasts on health and science to check out this summer

STAT

Summer is officially here, and whether you’re relaxing in the great outdoors or riding out a heat wave inside, STAT’s annual book and podcast list has you covered with a bevy of titles to check out. Read on for recommendations from the likes of FDA Commissioner Robert Califf, former CDC Director Rochelle Walensky, and former White House Covid-19 response coordinator Ashish Jha.

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Rallying in RSV vaccine race, Pfizer gains contract win over GSK in the UK

Fierce Pharma

After losing round one of its respiratory syncytial virus (RSV) vaccine bout with GSK, Pfizer is rallying. | After losing round one of its respiratory syncytial virus (RSV) vaccine bout with GSK, Pfizer is rallying. And what better way to do it than to win a major contract in your rival’s home country? The U.K. government has selected Pfizer to supply 5 million doses of its RSV shot Abrysvo over the next two years.

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We want your feedback!

pharmaphorum

Take part in the pharmaphorum reader survey 2024 and share your views on the latest trends and developments in the pharmaceutical industry. Your input helps us tailor our publication to meet your needs.

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‘A mixed bag’: Fifth Circuit rules on ACA preventive services legal case

Fierce Healthcare

The Fifth Circuit Court of Appeals has issued a decision in a major legal case that observers have said could fundamentally alter the preventive services provision in the Affordable Care Act. | The Fifth Circuit Court of Appeals has issued its ruling on Braidwood Management v. Becerra, a case that has wide-ranging implications on millions of Americans.

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Should you eat sourdough if you have diabetes?

The Checkup by Singlecare

People with diabetes need to be mindful of what foods and drinks they consume each day since the wrong combination of nutrients could lead to short-term problems, like blood sugar imbalances, as well as long-term problems, like higher risk of obesity , high cholesterol, high blood pressure, and heart disease. “The main [consideration] for people with diabetes is to maintain the right macronutrient balance and avoid high glycemic foods, including refined carbohydrates,” says Inna Melamed , Pharm.

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Surgeon general declares gun violence a public health crisis

STAT

Firearm violence is officially a public health crisis in the U.S. — Surgeon General Vivek Murthy says so. In a new advisory published on Tuesday, Murthy calls attention to the health toll of gun violence, describing the size of the crisis while laying out a roadmap of research and policy interventions to curb its effects. “My hope is that framing just the profound impact and pervasive impact of gun violence in our country … can firmly take it out of the realm of politics and

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Daiichi’s lung cancer ADC rejected by FDA in blow to first project under Merck partnership

Fierce Pharma

In the second setback for the HER3 field in days, the FDA has rejected Daiichi Sankyo’s Merck & Co.-partnered antibody drug conjugate (ADC) patritumab deruxtecan. | In the second setback for the HER3 field in days, the FDA has rejected Daiichi Sankyo’s Merck & Co.-partnered antibody drug conjugate patritumab deruxtecan.

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FDA clears Argenx’ Vyvgart Hytrulo for rare disease CIDP

pharmaphorum

Netherlands biotech Argenx has a second FDA approval for its FcRn inhibitor Vyvgart Hytrulo, adding a new indication in chronic inflammatory demyelinating polyneuropathy (CIDP) for a drug that it hopes could find a use in more than a dozen diseases.

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Hospitals' merger-fueled price increases force local employers to lay off staff, researchers warn

Fierce Healthcare

Higher care costs directly following a hospital merger have a downstream effect of local employers laying off a portion of their workers, according to a new National Bureau of Economic Researc | A new analysis ties merger-driven hospital price increases to higher employer insurance premiums and subsequent headcount reductions.

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Moderna’s RSV Vaccine Could Have Further Implications for mRNA Technology

Pharmacy Times

The recent approval could further the use of mRNA technology across other indications.

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Stop blindly allowing MA plans to use AI to deny care, lawmakers urge Biden administration

STAT

A bipartisan group of lawmakers is urging the Biden administration to prohibit Medicare Advantage insurers from using artificial intelligence tools to deny care until it completes a systematic review of their accuracy and effects on patients. In a letter sent Tuesday, the lawmakers cited a STAT investigation in calling on the Centers for Medicare and Medicaid Services to beef up oversight of AI and algorithmic tools that discriminate against old and sick patients.

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AbbVie's Duopa successor in Parkinson's rejected again after FDA flags third-party manufacturer issues

Fierce Pharma

A little over a year after being slapped with an FDA rejection, AbbVie has hit another regulatory wall in its bid to debut a more convenient Parkinson’s disease successor to its established fo | A little over a year after being slapped with an FDA rejection, AbbVie has hit another regulatory wall in its bid to debut a more convenient Parkinson’s disease successor to its established formulation of carbidopa and levodopa.

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AstraZeneca’s Tagrisso approved in Japan for lung cancer treatment

Pharmafile

AstraZeneca has announced that Tagrisso (osimertinib) in combination with pemetrexed and platinum-based chemotherapy has been approved in Japan for the first line treatment of adult patients with locally advanced or metastatic epidermal growth factor receptor-mutated (EGFRm) non-small cell lung cancer (NSCLC) whose tumours have exon 19 deletions or exon 21 mutations.

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Where UnitedHealthcare is seeing cost savings in its Surest plan

Fierce Healthcare

UnitedHealthcare is betting big on its Surest unit as the insurer releases new data on where the plan has seen success in the past several years. | UnitedHealthcare is betting big on its Surest unit as the insurer releases new data on where the plan has seen success in the past several years.

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