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Treatment options for Crohn’s disease expand after Rinvoq approval

Pharmaceutical Technology

The US Food and Drug Administration (FDA) has approved AbbVie’s Rinvoq (upadacitinib) for patients with Crohn’s disease who do not respond to TNF blockers, a common immune suppressant treatment for the condition. In patients with severe symptoms, a dosage of 30mg can be considered.

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Contamination Trends & Proposed Solutions

ISPE

In the remaining 17 studies, many contaminants were potent prescription-only medications such as antihypertensive drugs including hydrochlorothiazide, olmesartan, and enalapril; anticancer drugs including vincristine; and immune-modulating drugs such as azathioprine.