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Novel vaccine delivers significant survival in lung cancer trial

European Pharmaceutical Review

A T-cell epitope cancer vaccine significantly improved overall survival in non-small cell lung cancer (NSCLC) compared to chemotherapy, Phase III data published in Annals of Oncology has shown. percent with chemotherapy. The cancer vaccine offered an overall survival of 11.1 months for chemotherapy.

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Vaccine demonstrates benefit in delaying cancer relapse

European Pharmaceutical Review

A lymph node-targeted cancer vaccine has shown potential to prevent relapse of KRAS-mutated pancreatic and colorectal cancers in patients who have had surgery, according to a Phase I trial led by US researchers. Patients were given no more than 10 doses of the ELI-002 cancer vaccine targeted toward KRAS G12D and G12R mutations. “It

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Integrating personalised colorectal cancer vaccines into the evolving treatment landscape

Hospital Pharmacy Europe

The idea of cancer vaccines is not new, but Dr Victoria Kunene, consultant medical oncologist at Queen Elizabeth Hospital Birmingham, UK, is leading the charge in their latest iteration: personalised preventative and therapeutic mRNA vaccines against colorectal cancer.

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Takeda gets a win for its Wave1 pipeline, as Exkivity nabs FDA approval

pharmaphorum

The US regulator has cleared the tyrosine kinase inhibitor (TKI) as a second-line treatment for locally advanced or metastatic non-small-cell lung cancer (NSCLC) patients whose tumours have EGFR exon20 insertion mutations, after first-line chemotherapy.

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Five for Friday November 1: Celebrating Success in Advancing Medication Use Quality

PQA

We are excited to host members next week at the 2024 PQA Leadership Summit and PQA Convenes: Quality Medication Use in Rare Disease at the Renaissance Arlington Capital View Hotel in Arlington, Va. We also highlight our members' perspectives on health outcomes, oral oncolytics and vaccination recommendations.

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Microbiome therapies: a maturing movement

European Pharmaceutical Review

difficile infection by the end of 2024 and will be announcing first patient dosed in the Phase II clinical trial of VE202 for ulcerative colitis (UC) shortly too. How do you envision microbiome therapies complementing existing cancer treatments, such as chemotherapy and immunotherapy?

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FDA gives Ferring go-ahead for Adstiladrin gene therapy manufacturing

Pharmaceutical Technology

The company aims to then increase supplies in 2024. Common treatment options for the condition include bladder removal surgery, chemotherapy and/or administration of the BCG vaccine in the bladder. Ferring plans to begin Adstiladrin production in the H2 2023, as part of an initial rollout in the US.

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