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Pharmacovigilance deep dive: risk minimisation measures

European Pharmaceutical Review

This can be achieved by reducing the burden of adverse reactions or by optimising benefits through patient selection (eg, contraindications, recommendations of use, warnings, concomitant medicine[s], or certain test parameters) and treatment management (eg, specific dosing regimen, relevant testing, patient follow-up).

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Is compounded semaglutide safe?

The Checkup by Singlecare

That has led to some people taking it off-label (for a non-FDA-approved use) for weight lossat least until the FDA approved Wegovy specifically for weight loss in 2021. A compounded drug is any formulation of a drug that has not been produced by its original manufacturer under an official generic or brand-name label.

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Mounjaro interactions to avoid

The Checkup by Singlecare

Drug interactions | Food interactions | Other interactions | Avoiding interactions | When to see a doctor Mounjaro (tirzepatide) is gaining popularity as a treatment for Type 2 diabetes mellitus and off-label for weight management. Cases of diabetic retinopathy with tirzepatide use were noted in a 2021 study.

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Can you use metronidazole for cats?

The Checkup by Singlecare

Although not FDA-approved for animals, metronidazole is used off-label in cats when prescribed in veterinary medicine. She says metronidazole is a viable treatment option for a cat with no previous adverse reactions to the antimicrobial medication. When should metronidazole be avoided in cats?

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How long does it take for trazodone to work?

The Checkup by Singlecare

Results from a 2021 review of clinical trials showed that people with major depressive disorder (MDD) reported significant improvement in as little as one week. Anxiety Unlike depression, anxiety is an off-label use for trazodone. The same 2021 review found that patient improvements weren’t significant after seven days but after 21.

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9 Sneaky Thyroid Toxins Hiding in Your Home

The Thyroid Pharmacist

to fluoride in my tap water, to hidden mold in my home, to my shampoo and deodorant (have you ever read those labels?!), 16] Even more concerning, of the 133 different VOCs found across all tested products, only one, ethanol, was actually listed on any label! From indoor pollutants like formaldehyde (yes, really!),

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Jardiance for heart failure: How it works, effectiveness & more

The Checkup by Singlecare

In 2021, it was approved to treat adults with heart failure and reduced ejection fraction , which happens when the heart’s left ventricle isn’t pumping blood as well as it should when it contracts. Do not take Jardiance for heart failure if you have had a prior allergic hypersensitivity reaction, including angioedema, to the drug or class.