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mRNA vaccine trial shows efficiency in older adults with RSV

European Pharmaceutical Review

To date, most solicited adverse reactions were mild or moderate. The most commonly reported solicited adverse reactions in the mRNA-1345 group were injection site pain, fatigue, headache, myalgia, and arthralgia. In August 2021, mRNA-1345 gained Fast Track designation in adults over 60 years old.

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FDA approves first gene therapy for Haemophilia B

European Pharmaceutical Review

Sponsorship of the clinical trials transitioned to Australian biopharma company CSL after it acquired global rights to commercialise the treatment in May 2021. The most common adverse reactions (AR) associated with Hemgenix included liver enzyme elevations (transaminitis), headache, mild infusion-related reactions and flu-like symptoms.

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Pharmacovigilance deep dive: risk minimisation measures

European Pharmaceutical Review

This can be achieved by reducing the burden of adverse reactions or by optimising benefits through patient selection (eg, contraindications, recommendations of use, warnings, concomitant medicine[s], or certain test parameters) and treatment management (eg, specific dosing regimen, relevant testing, patient follow-up).

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What are the side effects of black seed oil?

The Checkup by Singlecare

Allergic reactions Hypoglycemia (low blood sugar levels) Elevated liver enzymes Kidney function decline Bleeding Overdose toxicity How soon do black seed oil side effects start? The onset time of adverse reactions to black cumin seed oil has not been elucidated to date.

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US FDA approves Amgen-AstraZeneca’s Tezspire for asthma treatment

Pharmaceutical Technology

It was initially FDA-approved in December 2021 and is claimed to be the only biologic approved to treat severe asthma with no phenotype or biomarker limitation. Pharyngitis, arthralgia, and back pain are the most common adverse reactions of the antibody.

FDA 59
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EC approves Libtayo® for metastatic cervical cancer

European Pharmaceutical Review

In March 2021, the trial was halted early due to highly significant overall survival (OS) rates in squamous cell carcinoma (SCC) patients. Immune-mediated adverse reactions (ARs) occurred in 21 percent of patients treated with Libtayo ® and led to permanent discontinuation in 4.6 to 0.84; p=0.00011). months Libtayo ® , 8.8

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Can you use metronidazole for cats?

The Checkup by Singlecare

She says metronidazole is a viable treatment option for a cat with no previous adverse reactions to the antimicrobial medication. Dr. Baker says this includes when a cat has known sensitivity or previous adverse reaction to metronidazole. When should metronidazole be avoided in cats?

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