The Checkup by Singlecare

MARCH 18, 2025

Antioxidants are often associated with a healthy immune system, but they may also stave off disease by protecting cells from damage caused by free radicals. Red raspberry leaves are rich in tannins (a chemical compound) and flavonoids (a plant pigment), which both have antioxidant properties, according to research in Antioxidants journal.

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Compounding Immunization FDA 80

pharmaphorum

AUGUST 5, 2022

MiroBio was formed in 2019 to develop checkpoint agonist antibodies for autoimmune and inflammatory disorders that can be used to apply the “natural brakes” of the immune system. 7 integrin, with three candidates in early-stage clinical development.

Immunization 105

Immunization 105

Druggist

AUGUST 8, 2020

Cell- or recombinant-based Vaccines an A/Hawaii/70/2019 (H1N1)pdm09-like virus; an A/Hong Kong/45/2019 (H3N2)-like virus; a B/Washington/02/2019 (B/Victoria lineage)-like virus; and a B/Phuket/3073/2013 (B/Yamagata lineage)-like virus. Flu season 2019/2020 ended on 31/03/2020. When did flu season end 2020?

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Vaccines Community Pharmacies Immunization Nursing Homes 98

pharmaphorum

JANUARY 18, 2021

Quadri, formerly Merck’s head of medical and scientific affairs, immune oncology, has been charged with one count of theft of trade secrets and one count of unauthorised transmission of trade secrets, some relating to the multi-billion dollar cancer immunotherapy Keytruda (pembrolizumab).

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Documentation Immunization Pharmaceutical Companies Pharmaceutical Companies 95

pharmaphorum

JULY 6, 2021

While these types of tests are important, they don’t tell the whole story, as they can’t provide information on whether an individual has built an immune response to COVID-19, either through vaccination or through a previous infection. This is where antibody tests come in. ” . . The Importance of Antibody Certificates.

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Immunization Vaccines 111

European Pharmaceutical Review

DECEMBER 12, 2023

He discusses why NK cell therapy’s ability to generate ‘synthetic immunity’ in the body means this modality holds potential as an anti-cancer treatment. We specialise in the development of new cutting-edge immunotherapies , based on the use of therapeutic antibodies capable of activating the immune system to fight cancer.

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Immunization Chemotherapy Pharmaceutical Companies Pharmaceutical Companies 124

European Pharmaceutical Review

AUGUST 2, 2023

This is an additional ingredient designed to trigger a stronger immune response. The vaccine demonstrated a strong immune response in the trial. In a clinical trial, this vaccine was shown to faciliate a strong immune response against the Omicron BA.1 1 variant, in addition to the original 2020 strain.

Vaccines 98

Vaccines Immunization 98

pharmaphorum

JUNE 16, 2022

The result isn’t a big surprise – Roche terminated two phase 3 trials of crenezumab in people with prodromal to mild sporadic Alzheimer’s in early 2019 after interim analyses found it would be futile to continue – but is another blow to the amyloid hypothesis.

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Immunization 111

European Pharmaceutical Review

MARCH 19, 2024

This pathway works in the innate immune system to sense cytosolic DNA by triggering a STING-dependent inflammatory response. In September 2019, IFM Due entered into an option and collaboration agreement with Novartis, who agreed to finance IFM Due’s research and development costs for the cGAS-STING programme.

Immunization 105

Immunization 105

Druggist

AUGUST 8, 2020

The prices for private flu jabs 2020/2021 service are as follows: Pharmacy chain Flu season 2020/2021 Flu season 2019/2020 Tesco Pharmacy £9 £9 Boots Pharmacy £13.99 £12.99 Flu season 2019/2020 ended on 31/03/2020. Available at: [link] Accessed on 07/08/2020 NHS England (2019). Asda Pharmacy £8 £7 Lloyds Pharmacy £12.99 £11.50

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Health and Personal Care Stores Vaccines Community Pharmacies Immunization 98

European Pharmaceutical Review

MAY 17, 2023

The viral therapy “aims to awaken the patient’s immune system and trigger a healing from within,” Dr Fueyo commented. After injection, patients that respond well develop inflammation inside the tumour, triggering an immune response that first kills the virus.” This makes it difficult to treat the cancer with immunotherapy.

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Immunization Chemotherapy 98

pharmaphorum

JANUARY 10, 2023

Since then, the two partners have developed multiple AI-based applications including a platform for selecting neoantigens for use in individualised cancer vaccines and an early warning system for high risk SARS-CoV-2 variants based on how well they can evade the immune system and their transmissibility.

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Immunization Vaccines 116

pharmaphorum

JUNE 21, 2021

It would be easy to forget that back in 2019, BioNTech was an early-stage biotech firmly focused on cancer vaccines, before being catapulted onto the world-stage with its COVID-19 shot.

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Vaccines Immunization 145

pharmaphorum

APRIL 28, 2021

Between just February and May 2020, submissions to Elsevier’s journals alone went up by 58% compared to the same period in 2019. “Text mining was also able to highlight new insights into the mechanisms of pancreatic cancer’s immune evasion, which refers to cancer cells’ ability to evade an immune response” .

Immunization 105

Immunization 105

pharmaphorum

JUNE 15, 2022

Cytokines have long been investigated for their potential as cancer treatments – selectively stimulate tumour-fighting immune cells – with varying levels of success. The company came to Boehringer’s attention in 2019, when it took part in the drugmaker’s BI Innovation Prize competition.

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Immunization Vaccines 98

European Pharmaceutical Review

NOVEMBER 18, 2022

This is almost three times the 2019 market volume (5.8 billion), nearly three-and-a-half times the 2019 market value ($38 billion). Achieving Immunization Agenda 2030 goals. The document showed that in 2021, approximately 16 billion vaccine doses, worth $141 billion, were supplied across 47 vaccines and 94 manufacturers.

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Vaccines Immunization Documentation 98

European Pharmaceutical Review

JULY 12, 2022

By binding to both CD19, an antigen expressed on B-cells, and to the CD3 receptor on T-cells, TNB-486 activates and recruits T-cells to CD19-expressing tumours where they can elicit an immune response. “By The post AstraZeneca to acquire TeneoTwo and its blood-cancer therapeutic appeared first on European Pharmaceutical Review.

Immunization 98

Immunization Chemotherapy 98

European Pharmaceutical Review

JULY 13, 2023

The field of immunotherapy is constantly evolving with the ultimate goal to develop new treatments that help the body’s immune system fight cancer. Immune cells, such as T cells and natural killer (NK) cells, have the inherent ability to combat diseases, including cancer, but are often inhibited by the body’s own suppressive mechanisms.

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Immunization Hospitals FDA 98

pharmaphorum

APRIL 8, 2022

Once within the tumour, it stimulates receptors on immune cells to mount an attack on the cancer. It was launched as Intron A by Schering-Plough (now Merck & Co) in the 1980s before being discontinued by the company in 2019 based on evaluation of its clinical activity and the emergence of alternative therapies.

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Immunization 105

pharmaphorum

MARCH 11, 2021

VX-880 (formerly known as STx-02) derives from Vertex’ near $1 billion acquisition of Semma in 2019, and has started enrolling patients in a phase 1/2 study in the US. As this won’t be used in the initial phase 1/2 trial, patients will have to receive immunosuppressive drugs to dampen down the immune response.

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FDA Immunization 98

pharmaphorum

MARCH 9, 2021

SARS-CoV-2 is likely to stay endemic in the human population for the foreseeable future, ExeVir noted, with variants capable of evading immunity the most likely cause of the disease in the future as global vaccination programmes begin to take effect. Ablynx, which is now a subsidiary of Sanofi following a $4.8

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Immunization Vaccines FDA 98

pharmaphorum

FEBRUARY 3, 2021

The emergence of novel base editing technologies that do not generate double-strand breaks (DSBs) offer a promising and safer alternative to fine-tune the next generation of immune cell therapies, especially as our need to perform complex multi-gene alterations increases. Another area for potential improvement is the source of immune cells.

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Immunization Vaccines 98

pharmaphorum

AUGUST 31, 2022

Kaiku’s DPPM platform has also attracted the attention of other big pharma groups, including Roche which has been working with the company since 2019 on personalised support modules for patients taking its PD-L1 inhibitor Tecentriq (atezolizumab).

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Chemotherapy Immunization Hospitals 116

European Pharmaceutical Review

APRIL 25, 2023

This signals the cell to the immune system and so it targets and kills the myeloma cell. A promising treatment for myeloma DVD was first rolled out in 2019 after it was approved through the Cancer Drugs Fund.

Immunization 98

Immunization 98

European Pharmaceutical Review

JANUARY 26, 2024

It is a key component of human vaccines for shingles, malaria, coronavirus disease 2019 and others under development.” Bioengineering vaccine adjuvants The paper explained: “QS-21 is a potent vaccine adjuvant currently sourced by extraction from the Chilean soapbark tree. Martin et al. Martin et al.

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Vaccines Compounding Immunization 98

pharmaphorum

MARCH 4, 2022

settlement deal proffered last year by the family in return for immunity from current and future civil lawsuits accusing them of contributing to the opioid epidemic. The US saw nearly half a million deaths from overdoses between 1999 and 2019, according to the US Centers for Disease Control and Prevention (CDC).

Immunization 98

Immunization 98

pharmaphorum

JUNE 27, 2022

Most people are able to shake off HBV infection over time, with drug therapy reducing vial levels to the extent that the immune system can keep the virus under control. The drug is designed to target viral DNA directly, which could give it a chance of targeting all traces of the virus in the body.

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Immunization 124

pharmaphorum

FEBRUARY 16, 2021

In 2019, Novartis also bought into the category via a $310 million takeover of IFM Therapeutics, which is developing NLRP3 drugs for atherosclerosis and non-alcoholic steatohepatitis (NASH), while UK startup NodThera raised $55 million last year for its own NLRP3 programme, eyeing NASH and diabetes.

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Immunization 119

Pharmaceutical Technology

MAY 25, 2023

The results from a trial, published in The New England Journal of Medicine , found the vaccine was associated with a strong immune response and good safety profile. The response was more powerful than that generated by MenACWY-D – a licensed quadrivalent meningococcal vaccine marketed by GSK.

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Vaccines Immunization 78

European Pharmaceutical Review

SEPTEMBER 22, 2023

The vaccination of patients with AN1792 led to the activation of their immune systems, which started producing endogenous anti-Abeta antibodies. Therefore, active immunotherapy to trigger the immune system to produce sustained levels of endogenous antibodies has now become far more attractive.

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Immunization Vaccines Communication Labelling 97

pharmaphorum

JANUARY 3, 2023

The most prominent of such therapies are immune checkpoint inhibitors, such as the PD-1/PD-L1 therapies that have become some of the best-selling treatments across the industry. What did change was the use of chemotherapy (26% in 2015 and 16% in 2019), and the increase in the delivery of immunotherapy (5% in 2015 and 18% in 2019).

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Chemotherapy Immunization Hospitals 105

pharmaphorum

SEPTEMBER 22, 2022

When exposed to a virus, one’s immune system develops antibodies in response to foreign antigens, with or without a vaccine. However, a vaccine trains the immune system to recognise that familiar virus and kill it more rapidly. Osivax’s technology, oligoDOM, trains the T-cell immune response to recognise the nucleoprotein.

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Vaccines Immunization 97

pharmaphorum

SEPTEMBER 22, 2021

Its lead project is a T-cell receptor (TCR)-like antibody against an HLA molecule associated with intracellular protein NKG2A, an immune checkpoint. Inhibiting NKG2A is thought to restore the activity of natural killer cells and T cells against cancer. Boehringer’s activity in this area hasn’t all been additive though.

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Vaccines Immunization 92

pharmaphorum

JANUARY 7, 2022

That initial collaboration resulted in Sanofi licensing in a first drug candidate in 2019 for oncology and inflammatory diseases and – given the scale of the expanded agreement – the big pharma was clearly impressed by the relationship. It’s not the only one either.

Immunization 110

Immunization 110

pharmaphorum

NOVEMBER 26, 2020

The two companies have been working together in this area since 2019, but BioNTech has opted to double down on the alliance with a revised agreement focusing on new immunotherapies for cancer and infectious diseases.

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Vaccines Immunization 105

pharmaphorum

APRIL 22, 2022

AP-013 started in June 2019 and was heavily impacted by the COVID-19 pandemic however, with too few patients recruited to allow it to assess the effect of Ampion on other measures such as joint function. .”

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FDA Immunization 111

pharmaphorum

JULY 21, 2022

The London-based company was founded by venture capital firm Medicxi in 2019, but has now come out of stealth mode with financial backing of €18 million and a platform based on a ‘molecular clamp’ technology developed by researchers at the University of Queensland (UQ) in Australia.

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Vaccines Immunization 105