IQVIA report assesses the impact of illegal online pharmacies
Drug Store News
MAY 12, 2023
Between 2019 and 2022, the number of prescriptions dispensed annually through IOPs increased from 64 to 85 million at a compounded annual growth rate of 10%.
STAT+: ‘Learning each other’s language’: FDA, patent office seek to work together to lower drug prices
STAT
DECEMBER 7, 2023
In 1997, Celgene obtained a key patent for what would become a blockbuster blood cancer treatment, giving it a monopoly until 2019. Not long after the patent was awarded, the company leveraged federally funded research and began investigating different forms of the compound, called Revlimid.
FDA 
125
125 Join 5,000+
Insiders
Sign Up for our Newsletter
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Trending Sources
Key vaccine adjuvant biosynthesised
European Pharmaceutical Review
JANUARY 26, 2024
It is a key component of human vaccines for shingles, malaria, coronavirus disease 2019 and others under development.” Bioengineering vaccine adjuvants The paper explained: “QS-21 is a potent vaccine adjuvant currently sourced by extraction from the Chilean soapbark tree. Martin et al. Martin et al.
Vaccines 98
98 
Do Blueberries Help Older People with Memory?
The People's Pharmacy
MARCH 30, 2023
Each day the blueberry powder provided 302 mg of anthocyanins, the purple and red compounds in blueberries. In one study in rats, the animals that performed poorly on a water maze test significantly improved their performance after six months of blueberry supplementation in their chow ( Journal of Gerontology, A, July 2019 ).
Compounding 76
76 Compounding 76
76 
Boehringer backs AI-powered anti-infective startup ArrePath
pharmaphorum
MARCH 7, 2022
The Princeton, New Jersey-based startup will use the funding to develop its artificial intelligence and imaging based drug discovery platform, used to identify compounds with new and under-exploited mechanisms of action. million deaths a year, according to the 2019 Gram Report. Dr Zemer Gitai.
Compounding 137
137 Compounding 137
137 
HPM Welcomes 15-Year DOJ Veteran, John W.M. Claud, to the Firm
The FDA Law Blog
NOVEMBER 15, 2022
He also held leading roles in DOJ’s response to multiple significant national health crises, including the COVID-19 pandemic, the 2019 EVALI vaping crisis, and the 2012 New England Compounding Center fungal meningitis outbreak.
Compounding 52
52 
Does coffee affect your cholesterol?
The Checkup by Singlecare
DECEMBER 18, 2023
Coffee itself doesn’t contain any cholesterol, but its natural oils contain kahweol and cafestol , two chemical compounds that have the potential to raise cholesterol levels. In other words, yes, the chemical compounds in coffee can raise cholesterol, but the effect coffee has on your cholesterol depends on individual factors.
Compounding 105
105 Compounding 105
105 
Beckley Psytech raises $80m for psychedelic meds development
pharmaphorum
AUGUST 16, 2021
The Oxford-based company had originally hoped to raise $50 million from the series B, and the scale of the financing is further evidence that repurposing psychedelic compounds as potential therapies for neuro-psychiatric disorders is a hot topic in biopharma. Beckley – formerly known as Beckley Canopy Therapeutics – raised £7.4
Compounding 135
135 Compounding 135
135 
Gatehouse Bio and AstraZeneca to develop RNA therapeutics for heart failure
Pharmaceutical Technology
SEPTEMBER 9, 2022
Initially, the companies partnered to identify new targets for respiratory and cardiovascular diseases using Gatehouse Bio’s artificial intelligence (AI)-powered platform in December 2019. It is expected to expedite the development of a wide range of new therapeutics using the small non-coding area of the genome that is not explored.
Compounding 98
98 Compounding 98
98 
3D printing and personalised medicines: embracing innovative technologies
Hospital Pharmacy Europe
MARCH 21, 2024
Supporting the successful compounding of drugs with 3D printing processes has the potential to not only fulfil unmet patient needs but also drive efficiencies in hospital pharmacies. 7 This trial was followed in 2019 by the first evaluation of the use of 3D printing of medications in a hospital.
Hospitals 111
111 
9 foods high in estrogen
The Checkup by Singlecare
FEBRUARY 1, 2024
Foods high in estrogen Phytoestrogens are estrogen-like plant-based compounds and are the form of dietary estrogen obtained from foods we consume. The roles of estrogen and estrogen receptors in gastrointestinal disease, Oncology letters (2019). Molecules (2019). Naturally lignan-rich foods: A dietary tool for health promotion?,
Mayo Clinic 95
95 
How to approach die plate adhesion during tableting
European Pharmaceutical Review
OCTOBER 23, 2023
In most cases, formulation compounds represent a fixed starting point from which any changes can be implemented, whereas tableting process parameters as well as machine condition, can be managed and optimised to their best, combining the knowledge of the machine manufacturer with the experience of the pharmaceutical industry. Sugar Alcohols.
Compounding 98
98 Compounding 98
98 
Summer 2021 – Transforming Pharmacy Through Innovation and Superior Customer Experience
Omnicell
JANUARY 10, 2023
In the central pharmacy, our IVX Workflow management system , now supports decentralized compounding, enabling an sterile compounding workflow system now supports decentralized compounding, enabling an alternative way to compound new orders. healthcare system, compromising both patient and workforce safety.
Diving deeper into AI discovery, Sanofi signs 5-drug deal with Atomwise
pharmaphorum
AUGUST 17, 2022
The deal will see Atomwise identify, synthesize, and advance lead compounds for up to five drug targets that will then be exclusively Sanofi’s to develop. In 2019 they struck a major deal with China’s Hansoh pharmaceuticals. “At Additional payments will be tied to specific research, development, and sales milestones.
Compounding 95
95 Compounding 95
95 
June is National Safety Month
OctariusRx
JUNE 5, 2023
Compounded Drugs: Will your facility use compounded drugs? Is the pharmacy providing the compounded drugs an FDA registered 503B outsourcing facility ? According to a 2019 report from the U.S. According to a 2019 report from the U.S. For starters, we recommend getting the <800> HazRx phone app.
Compounding 58
58 
AI specialist Insilico raises $60m as more projects head to clinic
pharmaphorum
JUNE 7, 2022
The Hong Kong-based startup – one of an emerging crop of companies which are using artificial intelligence platforms to discover and design new therapeutic compounds – took its first drug into clinical trials in February.
Compounding 52
52 Compounding 52
52 
Does Medicare cover Ozempic?
The Checkup by Singlecare
MARCH 7, 2024
A separate study published in 2019 surveyed 68,353 pharmacies across 16,325 ZIP codes and concluded that independent pharmacies and small chains typically charge higher prices than larger chains. Consider a compounded version Compounding pharmacies mix the active ingredients in a drug themselves. One report by the U.S.
ADCs Pipeline Update: Avacta Partners with ADC Therapeutics
Roots Analysis
FEBRUARY 27, 2024
On November 1, 2019, Avacta Group and ADC Therapeutics have announced a collaboration agreement for the development of novel drug candidates. They are also more resistant than mAbs to changes in environmental pH and temperature. In nature, they are made by a group of bacteria known as actinomycetes.
Compounding 52
52 Compounding 52
52 
Trials leave Galapagos’ SIK programme looking under the weather
pharmaphorum
JULY 16, 2021
Galapagos has had to send its SIK inhibitor programme back to the drawing board after its lead compound GLPG3970 has failed two of three clinical trials, adding to a string of disappointments for the Belgian biotech. . The preclinical compounds are expected to move into the human testing stage next year.
Mayo Clinic 59
59 
Switzerland’s Synendos raises CHF 20m for CNS drug development
pharmaphorum
NOVEMBER 12, 2020
The company was founded as a spin-off of the University of Bern and Swiss research institute NCCR TransCure in April 2019, and is focused on the development of a new class of drugs that work on endocannabinoids, a type of neurotransmitter that bind to the receptors in the brain targeted by cannabinoid compounds.
Compounding 101
101 Compounding 101
101 
Will Honey and Chocolate Ease Your Cough?
The People's Pharmacy
JUNE 19, 2023
It is rich in phenolic compounds that have antioxidant activity ( Kavanaugh et al, Food Chemistry, Jan. 30, 2019 ). Research in guinea pigs shows that the cacao compound theobromine can suppress the cough reflex ( Usmani et al, FASEB Journal , Feb. What Is Manuka Honey? Manuka honey is from New Zealand. 16, 2017 ).
Compounding 64
64 Compounding 64
64 
Evaluating NMR relaxometry for antibody identification
European Pharmaceutical Review
SEPTEMBER 25, 2023
NMR relaxation methods distinguish between components (phases or compounds) that have different molecular mobilities For monoclonal antibodies, identification methodologies can employ chromatography, spectroscopy, isoelectric focusing, capillary electrophoresis and peptide mapping techniques. 2019; 57(10): 794–804. 2019; 57(10): 873–7.
Compounding 98
98 
Dr Reddy’s jumps on medical cannabis train, buying Nimbus Health
pharmaphorum
FEBRUARY 3, 2022
It said the medical cannabis market in Germany is valued at approximately €122 million, growing at around 25% last year and with a compound annual growth rate estimated at 55 % since the market was liberalised in 2017.
Compounding 119
119 
Low Dose Naltrexone and Hashimoto’s
The Thyroid Pharmacist
JUNE 30, 2023
Interview With Dr. Mark Mandel To learn more, I decided to interview Dr. Mark Mandel, PharmD, compounding pharmacist, LDN expert, and fellow Midwestern University Chicago College of Pharmacy grad, on the effects of LDN in people with Hashimoto’s and autoimmunity. The transdermal formulation is recommended for children with autism.
Compounding 98
98 
Astellas and Cullgen to develop small molecule protein degraders
Pharmaceutical Technology
JUNE 15, 2023
The deal gives Astellas the option to exclusively license its rights for clinical development and commercialisation for any protein degrader compounds developed within the lead programme. Since 2019, the company has raised $106m in three financing rounds to push the development of its uSMITE platform.
Compounding 52
52 Compounding 52
52 
Sosei nets $10m Pfizer milestone as diabetes/obesity drug starts phase 2
pharmaphorum
DECEMBER 21, 2022
The GLP-1 agonist was the first drug in the partnership – which spans multiple compounds and therapeutic categories – to be selected for clinical development in 2019. For now, Rybelsus will be in Pfizer and Sosei Heptares’ sights, but there’s no word from them yet on why PF-07081532 could offer an improved profile.
Compounding 52
52 Compounding 52
52 
June is National Safety Month
OctariusRx
JUNE 7, 2022
Compounded Drugs: Will your facility use compounded drugs? Is the pharmacy providing the compounded drugs an FDA registered 503B outsourcing facility ? According to a 2019 report from the U.S. According to a 2019 report from the U.S. For starters, we recommend getting the <800> HazRx phone app.
Compounding 52
52 
8 health benefits of mushrooms
The Checkup by Singlecare
JULY 12, 2023
They may fight cancer Although mushrooms are low in fat and calories, they are high in antioxidant plant compounds that may have cancer-fighting effects. Kelvas point out that Lion’s Mane mushrooms, a variety high in the compounds hericenones and erinacines, are believed to support brain health. According to the Harvard T.H.
Compounding 52
52 
8 health benefits of beets
The Checkup by Singlecare
FEBRUARY 14, 2023
Whatever you know it as—and however you prepare it, from sliced raw to juiced to pickled to roasted—the beet is a nutritional powerhouse, packed with vitamin antioxidants, anti-inflammatory compounds, heart-healthy nitrates, and a few other unexpected benefits.
Compounding 98
98 
Can You Lower Blood Sugar with Cinnamon?
The People's Pharmacy
APRIL 17, 2023
Polyphenols, compounds found in cinnamon as well as tea, coffee, grapes, wine, cocoa and berries, slow the absorption of glucose (sugar) from the digestive tract and stimulate insulin secretion ( Kim et al, Nutrients , Jan. Cinnamon can help lower blood sugar for people with type 2 diabetes ( Clinical Nutrition , April 2019 ).
Compounding 78
78 
Ipsen beefs up in oncology, buying US biopharma Epizyme
pharmaphorum
JUNE 27, 2022
billion takeover of Clementia Pharma in 2019 – and erosion of its sales for top-selling acromegaly and neuroendocrine tumour therapy Somatuline (lanreotide). “Furthermore, we are excited to bring on board epigenetic expertise and the SETD2 inhibitor, as well as several preclinical compounds into our portfolio.”
Compounding 110
110 
How long does it take for sea moss to start working?
The Checkup by Singlecare
OCTOBER 25, 2024
One 2019 study , for example, found that adults with obesity or who were overweight lost body weight and body fat mass after 12 weeks of supplementation with a type of red algae called Gelidium elegans , but only 78 adults were included in the study. Sea moss is chock full of plant-based compounds that give it its many potential benefits.
Compounding 93
93 
10 health benefits of yerba mate
The Checkup by Singlecare
AUGUST 9, 2023
A 2019 research analysis associated high levels of omega-6 with a reduced risk of heart disease, stroke, and death. And a 2019 meta-analysis linked fish oil-based omega-3 supplements with a reduced risk of heart attack and death from heart disease.
Compounding 98
98 
Digital health player UpHealth swells with three-way merger
pharmaphorum
NOVEMBER 24, 2020
The blank cheque company or ‘special purpose acquisition company’ (SPAC) that provides funding is GigCapital2, which raised $150 million in its public offering in June 2019. The merger is expected to be completed in the first quarter of 2021, subject to the usual closing conditions.
Packaging 137
137 
Formulation development outsourcing market to be worth over $60bn by 2030
European Pharmaceutical Review
AUGUST 17, 2022
billion by 2030, expanding at a compound annual growth rate (CAGR) of 7.2 For Biogen, this was a 75 percent increase in R&D expenditure from 2019. According to a recent report , the global formulation development outsourcing market size should grow to $61.4 percent from its 2022 value of $35.1
Compounding 96
96 
Contamination Trends & Proposed Solutions
ISPE
MARCH 8, 2023
5 , 8 Compounding pharmacies were commonly mentioned as sources of microbial cross-contamination, especially in the US. 9 , 15 This has led to compounding pharmacies completing high-volume activities such as mass repackaging, thereby increasing the risk of cross-contamination. Compounding Pharmacies: Who Is in Charge?”
Compounding 52
52 
Seagen wins Enhertu patent dispute with Daiichi Sankyo
pharmaphorum
APRIL 10, 2022
10,808,039) covering ADCs that include auristatin compounds coupled to an antibody via a linker molecule. billion licensing deal for the drug in 2019. Seagen claims Enhertu (trastuzumab deruxtecan) – an antibody-drug conjugate (ADC) targeting HER2 – infringes a patient it holds (No.
Compounding 52
52 
LifeArc commits £10m to fund repurposed chronic respiratory infection therapies
pharmaphorum
NOVEMBER 24, 2022
Dr Catherine Kettleborough, lead of the LifeArc Chronic Respiratory Infection Translational Challenge, said: “Repurposing an existing drug or compound is a faster way of getting new treatments to patients. In 2019, the charity received a windfall of nearly $1.3 Travel to hospital for regular check-ups is frequently needed.
Hospitals 59
59 
Cell Therapy Pipeline Update: Talaris Therapeutics Announces Initiation of Phase 3 Clinical Trial
Roots Analysis
FEBRUARY 28, 2024
The stem cell manufacturing market for CMO is expected to grow at compounded annual growth rate (CAGR) of 18% during the forecast period 2019 – 2030. Specifically, small and mid-sized players in this sector tend to outsource a substantial proportion of clinical and commercial-scale manufacturing processes to contract service providers.
Compounding 40
40 
The lingering menace of diethylene glycol / ethylene glycol adulteration
European Pharmaceutical Review
DECEMBER 13, 2022
2 The issue arose because sulfanilamide is an extremely bitter tasting drug and to taste-mask the elixir formulation for use in children, the compounding pharmacist used EG as it was a good solvent, sweet-tasting and cheap. 5 Both compounds are limited to ≤0.1 percent or 1,000 ppm. This is considered an essentially safe dose.
Compounding 105
105 
Collaboration with Janssen and Eli Lilly to address lack of paediatric medications
Pharmaceutical Technology
JANUARY 23, 2023
In addition to Skyrizi’s recent supplementary CD indication, both Tremfya and Skyrizi received US FDA approval in psoriasis in 2017 and in 2019, respectively. These developments were compounded by Lilly’s announcement that it has discontinued development of mirikizumab for psoriasis in April of last year.
Compounding 59
59 
Crowdsourced science refines AI prediction of clinical trial outcomes
pharmaphorum
JULY 21, 2021
In 2019, a team at Massachusetts Institute of Technology (MIT) in the US came up with just such a model, and found that it was able to perform “better than random” at predicting the outcome of a clinical trial or development programme. The results were interesting, but the team wanted to do better.
Data Entry 105
105 
Galapagos’ long-serving CEO Onno van de Stolpe to retire
pharmaphorum
AUGUST 31, 2021
His departure comes after a tricky period for Galapagos, which van de Stolpe alludes to in his retirement announcement, saying: “despite recent setbacks, we continue to progress a deep pipeline of novel target-based compounds, while the commercial roll-out of our first approved product is underway.”
Compounding 52
52 
Targeting tumours with novel radiopharmaceuticals
European Pharmaceutical Review
OCTOBER 19, 2023
With alpha particles, you must be very careful how the drug is made to ensure that the compound remains stable between manufacturing and use. Dr Hoppin began working with Dr John Babich and Noria Therapeutics in 2018, joining their board of directors in 2019 and supporting the subsequent creation and funding of subsidiary PSMA Therapeutics.
Chemotherapy 105
105 
Let's personalize your content