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Medicinal cannabis: the route to good manufacturing practice registration

European Pharmaceutical Review

After the substance became legal in the UK in 2018, pharmaceutical companies have faced numerous obstacles to attain a fairer position in the industry. Advising companies, he emphasised that those “manufacturing cannabis-based medicines should not underestimate the scale of the challenge.” He founded Celadon in 2018.

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HPLC-MS/MS for NDMA impurity determination in sartans

European Pharmaceutical Review

In 2018, one batch of the generic drug valsartan was recalled due to unacceptable levels of the nitrosamine impurity NDMA. Nitrosamine impurities are undesirable organic compounds with genotoxic, carcinogenic and mutagenic activity. This was the first of numerous recalls due to N -nitrosamine impurities in these types of drug.

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Building CO2-neutral, defossilised supply chains for chemicals

European Pharmaceutical Review

Organic compounds are arguably the foundation of the pharmaceutical industry. All traditional small molecule pharmaceuticals include carbon building blocks” Organic compounds are arguably the foundation of the pharmaceutical industry. Environ Sci Technol 2018, 52, 4, 1725–1734 [link].

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Actualising the power of antibody-drug conjugates as cancer therapeutics

European Pharmaceutical Review

7 A key differentiator of the company’s technology is that these platforms can engineer ADCs that reduce non-specific, target-independent toxicities in pre-clinical experiments, which potentially increases the drug’s tolerability for patients. The future of the ADC approach looks bright.

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The Best Probiotics for Hashimoto’s

The Thyroid Pharmacist

Allegedly, the inventor left the company, along with his proprietary recipe, and the product that the VSL #3 manufacturer has been making is different than the clinically tested product. Published 2018 Oct 29. Published 2018 Jul 17. Published 2018 Jul 10. Cai YJ, Wang F, Chen ZX, et al. J Neuroinflammation. 2017;8:1666.

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A history of Pfizer

pharmaphorum

It was at this time they set their site at Sandwich in the UK, initially just to finish processing compounds imported from America, but due to tariffs on imported products the company rapidly expanded the plant to accommodate producing medicines from scratch. Likewise, tanezumab, an anti-osteoarthritic, failed in trials.

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Evaluating NMR relaxometry for antibody identification

European Pharmaceutical Review

NMR relaxation methods distinguish between components (phases or compounds) that have different molecular mobilities For monoclonal antibodies, identification methodologies can employ chromatography, spectroscopy, isoelectric focusing, capillary electrophoresis and peptide mapping techniques. European Pharmaceutical Review.