Impact Pharmaceutical Services

AUGUST 9, 2022

The group successfully submitted a “pilot” eCTD submission to the Food and Drug Administration (FDA) and gained FDA approval to transmit submissions through the Electronic Submissions Gateway (ESG). During the last year, IMPACT has submitted several FDA meeting packages for this consultant as well.

FDA 40

FDA Packaging Documentation 40

European Pharmaceutical Review

FEBRUARY 22, 2023

Of the 175 new drugs approved by the US Food and Drug Administration (FDA) between 2016 and 2019, most were biologics. The payload is packaged inside a dissolvable needle, loaded within a microsyringe that is attached to a folded, self-inflating balloon. Biologics represent an increasingly large part of the pharmaceutical industry.

Immunization 105

Immunization Packaging Labelling FDA 105

ISPE

MARCH 8, 2023

Identification and Analysis of Contamination Trends Three major recall databases—those of the US FDA, the United Kingdom’s Medicine and Healthcare Products Regulatory Agency (UK MHRA), and Australia’s Therapeutic Goods Administration (TGA)—were searched to assess contamination trends in the past five years.

Compounding 52

Compounding Compounding Pharmacies Packaging FDA 52

Birth Control Pharmacist

SEPTEMBER 20, 2021

new combined oral contraceptive was approved by the FDA (Nextstellis®) in April 2021. In conclusion, Nextstellis is a recent FDA-approved oral contraceptive that offers patients another alternative for birth control. Nextstellis (Drospirenone and Estetrol) [package insert]. REFERENCES. Accessed June 25, 2021. 2020, [link].

Adverse Reactions 52

Adverse Reactions Packaging FDA Labelling 52

The Checkup by Singlecare

SEPTEMBER 28, 2023

Follow these steps to try nasal irrigation for congestion: Prepare the nasal rinse solution by mixing saline with distilled water per the package instructions. The FDA recently announced that the oral version of phenylephrine, a popular ingredient in some decongestants, is ineffective.

Compounding 105

Compounding Immunization Mayo Clinic Dosage 105

The Checkup by Singlecare

MAY 8, 2023

Tramadol has been available in the United States since 1995, but not until 2014 did it become a schedule IV controlled substance by the Food and Drug Administration (FDA) based on data suggesting abuse potential similar to other schedule IV opioids available at that time. What can I take in place of tramadol?

Controlled Substances 52

Controlled Substances Dosage Labelling FDA 52

ISPE

SEPTEMBER 11, 2023

4 , 5 Additionally, reducing shipping limitations—such as packaging, storage, and transportation durations—helps speed up patient access in certain instances while ensuring there is no negative impact to the product’s critical quality attributes (CQAs). FDA Official Warns Manufacturers of Common Problems Found in Aseptic Operations.”

Health and Personal Care Stores 52

Health and Personal Care Stores Vaccines Packaging Documentation 52

ISPE

MARCH 29, 2023

As part of the US Food and Drug Administration (FDA) QbD pilot 4 in 2005–2006, the need to convey how the control strategy is linked to the target product profile (TPP) and quality target product profile (QTPP) was discussed. Direct feedback from the US FDA on this pilot is shared in the discussion.

Documentation 52

Documentation Dosage Packaging Communication 52

ISPE

MARCH 29, 2023

As part of the US Food and Drug Administration (FDA) QbD pilot 4 in 2005–2006, the need to convey how the control strategy is linked to the target product profile (TPP) and quality target product profile (QTPP) was discussed. Direct feedback from the US FDA on this pilot is shared in the discussion.

Documentation 52

Documentation Dosage Packaging Communication 52

ISPE

AUGUST 29, 2022

For changes requiring approval before implementation, once the necessary information has been submitted across regions, each health authority must review the data package and documentation based on local requirements. 10. Published July 2014. laboratory notebooks, batch records, and technical reports) to submission documents (e.g.,

Documentation 52

Documentation FDA Communication Packaging 52

ISPE

JANUARY 11, 2023

August 2014. For example, the equipment for blending and packaging large-volume, high-viscosity formulations is complex, and the residues can be challenging to remove. Bethesda, MD: PDA and River Grove, IL: DHI Publishing, 2014. “Validation of Cleaning Processes (7/93): Guide to Inspections Validation of Cleaning Processes.”

Method Validation 52

Method Validation Documentation Packaging Compounding 52

The Checkup by Singlecare

MARCH 21, 2023

Today, it is approved by the Food and Drug Administration ( FDA ) for chronic musculoskeletal pain—like low back pain , neuropathic pain associated with diabetes mellitus , and fibromyalgia; it is used off-label for chemotherapy-induced peripheral neuropathy.

Dosage 52

Dosage Controlled Substances Labelling Packaging 52

The Thyroid Pharmacist

JULY 29, 2022

Back in 2014, I found that my Hashimoto’s flared up after using a particular lip gloss; once tested, it came back as containing arsenic! . This article of mine discusses 19 thyroid-toxic products that have been banned by the FDA. Published March 2014. 2014 Aug;7(8):813-823. Wildfire Emissions and Particulate Matter.

Health and Personal Care Stores 52

Health and Personal Care Stores Compounding Immunization Labelling 52

The Thyroid Pharmacist

OCTOBER 27, 2023

Follow package instructions. Follow package directions for each supplement. Sleep issues: I like to recommend Epsom salt baths, which contain magnesium that is absorbed through the skin (1 cup of salts per tub – follow package instructions, and don’t overdo it!), Published 2014 May 24. J Appl Microbiol. 2014;7:181-190.

Health and Personal Care Stores 99

Health and Personal Care Stores Immunization Compounding Packaging 99

ISPE

JULY 6, 2023

As of 2022, there were 15 drugs (see Table 1) manufactured using CM elements that have received FDA approval, with GSK, Pfizer, and Vertex owning approximately 60% of the market share, followed by Janssen/J&J with about 13%. Table 1: List of FDA-approved commercial products using CM elements.

HIV Treatment and Prevention Agents 52

HIV Treatment and Prevention Agents Dosage Pharmaceutical Companies Pharmaceutical Companies 52

The Checkup by Singlecare

DECEMBER 1, 2023

Plan B prescribing information shared by the Food and Drug Administration (FDA) lists heavier menstrual bleeding (31%), nausea (14%), lower abdominal pain (13%), fatigue (13%), dizziness (10%), and headache (10%) as the most commonly reported side effects in original clinical trials of Plan B. Plan B can be taken with or without food.

FDA 90

FDA Mayo Clinic Dosage Controlled Substances 90