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UNC team discovers interactions vital for hepatitis A virus replication

Pharmaceutical Technology

The team also found that the oral compound, RG7834, developed by Hoffmann-La Roche, hindered replication at a crucial step, preventing the virus from infecting liver cells. In addition, the research indicates that the compound was safe at the dosage level used in this research and the acute timeframe of the study.

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From Healing to Harm: The Unintended Consequences of Polypharmacy in Seniors

PharmD Live

The side effects can compound, resulting in a greater negative impact on a patient’s health than the individual effects of one medication alone. Healthcare providers review medication lists, adjust dosages, and coordinate care among multiple specialists. Neurology (2015). Anticholinergic Drug Exposure and the Risk of Dementia.

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Fixed-dose combination: Considerations for design, formulation, manufacturing and analysis

Pharmaceutical Technology

Understanding both the significant competitive advantages that FDC products can offer, and the difficulties and potential pitfalls associated with development and manufacturing of FDC drugs in oral solid dosage forms is a critical first step for companies exploring this approach. Of those 131 approved FDCs, 98 were oral dosage forms.

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Contamination Trends & Proposed Solutions

ISPE

5 , 8 Compounding pharmacies were commonly mentioned as sources of microbial cross-contamination, especially in the US. 9 , 15 This has led to compounding pharmacies completing high-volume activities such as mass repackaging, thereby increasing the risk of cross-contamination. 17 (2013): 1598–1609. 3 (2013): 253–257.

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11 benefits of black seed oil

The Checkup by Singlecare

Scientific studies have confirmed that thymoquinone, a compound found in black seed oil, is packed with antioxidants , along with antimicrobial, anti-inflammatory, and anti-cancer activity. However, thymoquinone , the active compound in the black cumin seed, has been shown to reduce the growth of certain cancer cells.

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14 remedies to get rid of congestion

The Checkup by Singlecare

Supplement with turmeric Curcumin is the main compound of the herb turmeric, and according to Dr. Garcia-Ibáñez, it works as a powerful antioxidant and anti-inflammatory. If you go the latter route, the recommended dosage is 500 mg two to three times daily for one to two weeks before you’ll be exposed to allergens. Harvard T.H.

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Quetiapine interactions to avoid

The Checkup by Singlecare

When taken with other drugs that cause QT prolongation, this risk is compounded. Drugs that increase the QT interval The QT interval is when the heart’s lower chambers contract and then fully relax. QT prolongation may occur as a side effect of a medication or a drug interaction. Quetiapine may prolong the QT interval.