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AC Immune claims half a win for tau drug in Alzheimer’s trial

pharmaphorum

Shares in AC Immune leaped today after the company said its tau-targeting Alzheimer’s disease candidate semorinemab hit one of its objectives in a phase 2 trial, although it missed another. Roche’s Genentech unit bought into the programme in 2012 and amended it three years later.

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GSK, Verily-backed Galvani starts trials of bioelectronic arthritis therapy

pharmaphorum

Lab studies have suggested that this type of stimulation can alter immune cells made in the spleen switching them from a pro-inflammation to an anti-inflammation state. Galvani is using its device to stimulate the splenic nerve, which sends signals to the spleen.

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Immuno-oncology market set to grow in billions, but access concerns remain

Pharmaceutical Technology

While the market was worth over $6 billion in 2012, this has now grown to nearly $48 billion only a decade later, said Avigayil Chalk, PhD, GlobalData’s Senior Oncology and Haematology analyst, at an immuno-oncology webinar held on May 23. was powered by the advent of immune-checkpoint inhibitors, added Chalk.

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The role of data science and text mining in the search for new therapies

pharmaphorum

“Text mining was also able to highlight new insights into the mechanisms of pancreatic cancer’s immune evasion, which refers to cancer cells’ ability to evade an immune response” . This was only discovered in 2012 and is a currently active area of research within pancreatic cancer.

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10 health benefits of shilajit

The Checkup by Singlecare

Inflammation is a natural response by the body’s immune system to protect itself from harmful bacteria or during an injury. Another 2012 article suggests that a formula containing shilajit and vitamin B complex may be effective against Alzheimer’s disease. Too much tau protein can trigger brain inflammation and brain tissue damage.

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AI drug discovery biotech AbCellera eyes record IPO

pharmaphorum

AbCellera is a specialist in applying artificial intelligence to drug discovery, specifically to sift through immune system data to find antibodies that can be developed as drugs. AbCellera was founded in 2012 and posted $28 million in revenue for the 12 months ending 30 September.

FDA 111
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New Legislation Would Cut Off Access To The Courts And Immunize FDA Actions From Timely Judicial Review

The FDA Law Blog

Senate Committee on Health, Education, Labor and Pensions (“Senate HELP”) is scheduled to take up legislation that could significantly limit access to the courts and immunize critical FDA decisions from timely judicial review. 112-144 (2012). Importantly, because FDA has sovereign immunity from damages claims, sponsors trapped in S.