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International regulation: the importance of quality assurance in drug development

European Pharmaceutical Review

Since the first ADC was approved by the EMA in 2012, they have generated a great deal of interest in the oncology field because of their potential to address many of the challenges of traditional chemotherapy options. Teams must also accept the variety of analytical procedures these regulatory agencies prefer.

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Ondansetron interactions to avoid

The Checkup by Singlecare

Therefore, any onset of symptoms should be managed by immediate communication with a healthcare professional. Some dosage forms of ondansetron contain sodium benzoate, a metabolite of benzyl alcohol. It is important to note that individuals may develop serotonin syndrome and serotonin toxicity on only a single serotonergic agent.

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Contamination Trends & Proposed Solutions

ISPE

2 , 16 , 17 , 18 One example is the switching of tributyltin azide with sodium azide and dimethyl formamide by Zhejiang Huahai Pharmaceuticals (ZHP) in 2012 to reduce waste and to increase yield in the production of angiotensin II receptor blockers, resulting in the formation of N-nitrosodimethylamine (NDMA), a known carcinogenic impurity.

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MTHFR, Hashimoto’s and Nutrients

The Thyroid Pharmacist

A 2012 study by Arakawa and colleagues of thyroid patients with Hashimoto’s and Graves’, found that polymorphisms – that is, gene variations that may lead to the abnormal expressions – were as common in autoimmune thyroid disease as they were in the normal population. [10] The answer is a bit complicated!

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Enabling Global Pharma Innovation: Delivering for Patients

ISPE

In addition, this article provides an explanation of the purpose and expected outcomes from the survey, subsequent plans for communicating the results from the survey across ISPE, and development of concrete proposals to address the sources of challenges and barriers to innovation. Published May 2012.

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Brain Fog and Hashimoto’s

The Thyroid Pharmacist

As a reminder, please consult with your practitioner to determine which supplements and dosages are appropriate for you. It also contains CDP choline, an active component of phosphatidylcholine, which comprises 30 percent of brain tissue and preserves brain cell membranes, protects memory, and facilitates neural communication.

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Muscle Wasting and Hashimoto’s

The Thyroid Pharmacist

While the body makes anabolic hormones naturally, and in some cases, bioidentical dosages can be prescribed safely to ensure that we are in a balanced anabolic state if we are deficient, there are great risks when the steroids are used in excessive doses to “bulk up,” as they push the body into a hyper anabolic state. 2012;Feb;51(1):1-18. [16]