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BMS’ Orencia gets FDA nod for GvHD thanks to real-world data

pharmaphorum

Bristol-Myers Squibb’s rheumatoid arthritis drug Orencia has been approved by the FDA to prevent graft versus host disease (GvHD), a serious complication of haematopoietic stem cell transplant (HSCT) used to treat leukaemias and other blood cancers. billion in the first nine months of the year.

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Early cell therapy successes start to turn the tide in lupus

Pharmaceutical Technology

In August 2021, Saphnelo, a type 1 interferon receptor antibody, became the first lupus treatment to be approved since GSK’s Benlyta (belimumab) won a regulatory nod in 2011. In lupus, the body’s immune system starts to attack its own cells. As per AstraZeneca's recent Q3 earnings, Saphnelo has yielded $69 million to date this year.

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Understanding the microbiome as an ‘overlooked critical organ’

pharmaphorum

PubMed cites 1,822 pieces of research relating to the microbiome in 2011, which grew to 25,153 published in 2021. As more research has been conducted, closer and unexpected links have been found between the microbiome of the gut, as one example, and other areas of the body, such as brain health and the immune system.

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Re-engineering proteins to develop novel immunotherapies

European Pharmaceutical Review

The field of immunotherapy is constantly evolving with the ultimate goal to develop new treatments that help the body’s immune system fight cancer. Immune cells, such as T cells and natural killer (NK) cells, have the inherent ability to combat diseases, including cancer, but are often inhibited by the body’s own suppressive mechanisms.

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BMS gets FDA OK for first LAG-3 checkpoint inhibitor

pharmaphorum

Bristol-Myers Squibb has won FDA approval for the first LAG-3 inhibitor drug ahead of its rivals in cancer immunotherapy including Merck & Co. Like PD-1, LAG-3 is a negative regulator of T cells, suppressing their activity against cancer cells, so when that brake is released the immune system can attack and kill tumours.

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How to stop taking omeprazole

The Checkup by Singlecare

Food and Drug Administration (FDA) to treat gastroesophageal reflux disease (GERD), duodenal ulcers, Helicobacter pylori infections ( H.Pylori ), benign gastric ulcers, erosive esophagitis, and conditions that cause excess stomach acid production (hypersecretory conditions). At prescription strengths, omeprazole is approved by the U.S.

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Top 9 Takeaways From 2232 People With Hashimoto’s

The Thyroid Pharmacist

Vitamin D supports the immune system by enhancing the pathogen-fighting effects of white blood cells, which are important parts of immune defense. Supplementing with vitamin D can especially help to improve mood and cognitive function during the winter months, as well as improve immune function. I recommend doses of 1.5