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Dr. Bernard Bihari is credited with making these discoveries about using naltrexone off-label, at lower doses. LDN was one of the first interventions that I had tried on my thyroid journey back in 2009. These include Crohn’s, MS, and Hashimoto’s, as well as other immune system-related conditions such as cancer and HIV/AIDS.
Its also used off-label to treat or slow the progression of various kidney conditions, including for patients with diabetes. One 2009 study of Type 1 diabetes suggested that 40 mg/day lowers blood pressure and urinary albumin excretion ratehow doctors test kidney functionmore effectively than 20 mg/day.
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