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Contamination Trends & Proposed Solutions

ISPE

The cases covered the same types of contaminants and impurities noted in Table 1: microbial contaminants, process-related im-purities, metal contaminants, packaging-related contaminants, drug cross-contamination, and an “unknown” category encompassing other contaminants associated with the manufacturing process, including those from cell culturing.

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Top 20 RNAi Therapeutic Companies Based on 2022 R&D Expenditure

PharmaShots

Founded Year: 2007 Total Employees: ~100 Headquarters: Pennsylvania, United States Market Cap: $477.1M The company strives to discover and develop therapeutic products under its business segments, including General Medicines, Specialty Medicines, and Vaccines. R&D Expenditure: $84.4M R&D Expenditure: $6.6B