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Paediatric oral compounding: expert insights from a global study

Hospital Pharmacy Europe

A new global study from the International Pharmaceutical Federation (FIP)s Pediatric Formulations Focus Group is the first to report current and global paediatric oral extemporaneous compounding practices. The FIP study aimed to identify current global paediatric oral extemporaneous compounding practices, challenges and needs.

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Contamination Trends & Proposed Solutions

ISPE

Microbial Contaminants From 2007 to 2021, 90 cases of contamination due to microorganisms were reported, with 61 caused by bacteria, 5 , 6 , 7 , 8 , 9 , 10 , 23 by viruses, 11 , 12 and 6 by fungi. 5 , 8 Compounding pharmacies were commonly mentioned as sources of microbial cross-contamination, especially in the US. 3 (2009): 313.

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Accommodating Multiple Modalities in the Same Facility

ISPE

From a regulatory perspective, the only products that are to be excluded are sensitizing agents, including penicillins and cephalosporins (beta-lactams); potentially genotoxic compounds; and potentially OEB 5 compounds where the risk assessment indicates the compound cannot be adequately controlled. Published 2007.

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Brain Fog and Hashimoto’s

The Thyroid Pharmacist

Compounded medications : If NDT medications do not seem like a good fit for you, compounded T4/T3 products offer another alternative. Thyroid compounds are usually prepared in the same physiological ratio that is found in NDT products. 2007 Oct 12;149(1):112-22. [17] 2007 Nov;98(5):960-8. Epub 2007 May 31. [46]

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Solutions for Constipation Relief

The Thyroid Pharmacist

Tegaserod : This medication was approved for IBS-C in 2002, but removed from the market in 2007 due to an increased risk of cardiovascular events. 63] Many of the benefits of ginger are due to gingerol and shogaol, compounds called gingeroids, which may also help with bloating, belching, and discomfort after meals. [64] 2020;11:25.

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Got Acid Reflux? And Hashimoto’s?

The Thyroid Pharmacist

9] When the body is exposed to an allergen, histamine production increases and turns on inflammatory processes to protect the body from that compound. Many of them do so by helping the gut to communicate with the central nervous system, essentially retraining it to move more efficiently. 2007; 85(5): 1185-96. Harvard Health.

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Histamine and Hashimoto’s

The Thyroid Pharmacist

1] In simple terms, when your body is exposed to a reactive compound, histamine increases and turns on inflammatory processes in order to protect the body from that compound. 2007; 85(5): 1185-96. She was fierce, fun, dedicated, and brilliant. References [1] Maintz L, Novak N. Histamine and Histamine Intolerance. 2] Thakkar MM.