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Navigating delivery challenges of nucleic acid therapeutics

European Pharmaceutical Review

According to the authors, self-amplifying RNA (saRNA) could be a next-generation vaccine platform, but it requires smart drug delivery vehicles to maintain the long-term stability and efficiency of the drug. The current NA dosage forms and novel DDSs have enabled the successful launch of NA therapeutics globally. Ingle et al.

Dosage 105
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Top 20 Radiopharma Companies Based on Market Cap

PharmaShots

Market Cap: $8.46M Founded Year: 2004 Total Employees: ~4 Headquarters: Texas, United States Stock Exchange: OTCMKTS QSam Biosciences is a clinical-stage biotech company focused on developing and commercializing targeted therapeutic radiopharmaceutical products for treating cancer and related diseases.

FDA 56
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Considerations for a Decentralized Manufacturing Paradigm

ISPE

POD is suitable for a wide range of products, including oral solid dosage forms, mAbs, and cell therapy. September 2004. Duplication enables rapid scale-up and scale-out, new facilities can be constructed in less than 12 months, and isolated operation avoids cross-contamination. Journal of Pharmaceutical Sciences 111, no.

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Regulatory Landscape for Raw Materials: CMC Considerations

ISPE

During the pandemic, the pharmaceutical industry faced challenges in the production of COVID-19 therapeutics and vaccines to meet global demand, as well as mitigation of drug shortages for non-COVID-19-related products, without compromising product quality or patient safety. 6 US Food and Drug Administration. Burke, S., Hammond, and T.